6-O-Methacrylate

Names

[ Name ]:
6-O-Methacrylate

[Synonym ]:
MFCD34471092

Biological Activity

[Description]:

6-O-Methacrylate, a trilobolide, is isolated from the leaves of Wedelia trilobata. 6-O-Methacrylate displays marked antimalarial activity, with IC50 of 8.9 μg/mL against P. falciparum parasite. 6-O-Methacrylate also has anti-tobacco mosaic virus (TMV) activity[1][2].

[Related Catalog]:

Research Areas >> Infection

[In Vitro]

6-O-Methacrylate (10 μg/mL) shows anti-TMV activities in the pretreated tobacco plants with inhibition rate of 59.6%[2].

[References]

[1]. That QT, et, al. Wedelolides A and B: novel sesquiterpene delta-lactones, (9R)-eudesman-9,12-olides, from Wedelia trilobata. J Org Chem. 2007 Sep 14;72(19):7102-5.

[2]. Li Y, et, al. Eudesmanolides from Wedelia trilobata (L.) Hitchc. as potential inducers of plant systemic acquired resistance. J Agric Food Chem. 2013 Apr 24;61(16):3884-90.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₃₀O₉

[ Molecular Weight ]:
450.48

6-O-Methacrylate

Names

Biological Activity

Chemical & Physical Properties

Related Compounds