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Maleimide-PEG2-NHS Ester

Names

[ CAS No. ]:
955094-26-5

[ Name ]:
Maleimide-PEG2-NHS Ester

[Synonym ]:
MAL-EG(2)-NHS 3-(2-(2-(3-MALEINIMIDOPROPANAMIDO)ETHOXY)ETHOXY)PROPANOIC ACID SUCCINIMIDYL ESTER
SM(PEG)2
Maleimide-NH-PEG2-CH2CH2COONHS Ester
Maleimide-PEG2-succinimidyl ester
Maleimidopropionyl-PEG2-CH2CH2COONHS Ester
3-[2-[2-[[3-(2,5-Dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxopropyl]amino]ethoxy]ethoxy]propanoic acid 2,5-dioxo-1-pyrrolidinyl ester
Maleimide-PEG2-NHS Ester

Biological Activity

[Description]:

Mal-amido-PEG2-NHS ester is a nonclaevable ADC linker containing a maleimide group and an NHS ester. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules[1][2].

[Related Catalog]:

Research Areas >> Others

[Target]

Noncleavable


[References]

[1]. Hansen AM, et al. Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae. Eur J Med Chem. 2019 Apr 15;168:134-145.

[2]. Zhang ge, et al. Preparation and application of FAPalpha activated polypeptide magnetic nanosphere compound used for diagnosis of tumors. CN105524141A

Chemical & Physical Properties

[ Density]:
1.41±0.1 g/cm3 (20 °C, 760 mmHg)

[ Melting Point ]:
90.0 to 94.0 °C

[ Molecular Formula ]:
C18H23N3O9

[ Molecular Weight ]:
425.39000

[ Exact Mass ]:
425.14300

[ PSA ]:
148.62000

[ Storage condition ]:
20°C

[ Water Solubility ]:
Slightly soluble (5.1 g/L) (25 ºC)

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29280000

Related Compounds