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N-Boc-piperazine-C3-COOH

Names

[ CAS No. ]:
959053-53-3

[ Name ]:
N-Boc-piperazine-C3-COOH

Biological Activity

[Description]:

N-Boc-piperazine-C3-COOH is a PROTAC linker, which refers to the alkyl/ether composition. Boc-N-piperazine-C3-COOH can be used in the synthesis of PROTAC PD-1/PD-L1 degrader-1 (HY-131183)[1].

[Related Catalog]:

Research Areas >> Inflammation/Immunology
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

Alkyl/ether


[References]

[1]. Cheng B, Ren Y, Cao H, Chen J. Discovery of novel resorcinol diphenyl ether-based PROTAC-like molecules as dual inhibitors and degraders of PD-L1. Eur J Med Chem. 2020;199:112377.

Chemical & Physical Properties

[ Molecular Formula ]:
C14H24N2O5

[ Molecular Weight ]:
300.35

[ Storage condition ]:
2-8°C

Related Compounds