N-(3-(4-bromophenyl)-propanoyl)-L-homoserine lactone

Names

[ CAS No. ]:
959613-39-9

[ Name ]:
N-(3-(4-bromophenyl)-propanoyl)-L-homoserine lactone

[Synonym ]:
4-bromo-N-[(3S)-tetrahydro-2-oxo-3-furanyl]-benzenepropanamide, LasR and TraR inhibitor, LuxR

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₁₄BrNO₃

[ Molecular Weight ]:
312.16

[ Storage condition ]:
−20°C

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Modulation of bacterial quorum sensing with synthetic ligands: systematic evaluation of N-acylated homoserine lactones in multiple species and new insights into their mechanisms of action.

J. Am. Chem. Soc. 129(44) , 13613-25, (2007)

Bacteria use a language of low molecular weight ligands to assess their population densities in a process called quorum sensing. This chemical signaling process plays a pivotal role both in the pathog...

Comparative analyses of N-acylated homoserine lactones reveal unique structural features that dictate their ability to activate or inhibit quorum sensing.

ChemBioChem. 9(3) , 389-400, (2008)

Bacterial quorum sensing is mediated by low molecular-weight signals and plays a critical role in both the pathogenesis of infectious disease and beneficial symbioses. There is significant interest in...