Sulfaquinoxaline sodium salt

Names

[ CAS No. ]:
967-80-6

[ Name ]:
Sulfaquinoxaline sodium salt

[Synonym ]:
Sodium sulfaquinoxaline
SULFQUINOXALINE SODIUM
Sodium [(4-aminophenyl)sulfonyl](2-quinoxalinyl)azanide
SULFAQUINOXAINESODIUM
MFCD00799608
SULFAQUINOXALINE SOD.
SULFAQUINOXALINE SODIUM CP2000
n'1-quinoxalin-2-ylsulphanilamide sodium salt
Einecs 213-526-2
EMbazin
SULFAQUINOXALINE SODIUM

Biological Activity

[Description]:

Sulfaquinoxaline sodium salt is an antibiotic which has activity against a broad spectrum of Gram-negative and Gram-positive bacteria.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial

Research Areas >> Infection

[Target]

Bacterial[1]

[In Vivo]

The antimicrobial Sulfaquinoxaline sodium salt has activity against a broad spectrum of Gram-negative and Gram-positive bacteria and is widely used in poultry production as therapeutic or prophylactic agent. Concentrations of Sulfaquinoxaline sodium salt that are higher than the drug’s maximum residue limit (MRL) (100 μg/kg) are found in the breast muscle until the 36th day of breeding in this study[1].

[Animal admin]

For the depletion studies, 240 1-day-old Cobb chicks are used. The chickens are housed in pens that contains 30 birds each (10 birds/m2) and are provided ad libitum access to water and non-medicated feed. The chickens are randomly allocated into four experimental groups, labeled from A to D, containing 80 birds each. Chickens in group A form the untreated control group, whereas those in group C are treated with 10 mg/kg bw of Sulfaquinoxaline sodium salt, which is administered via drinking water from the 32nd to 34th day of breeding[1].

[References]

[1]. de Assis DC, et al. Evaluation of the Presence and Levels of Enrofloxacin, Ciprofloxacin, Sulfaquinoxaline and Oxytetracycline in Broiler Chickens after Drug Administration. PLoS One. 2016 Nov 15;11(11):e0166402.

[Related Small Molecules]

Chemical & Physical Properties

[ Boiling Point ]:
551.1ºC at 760 mmHg

[ Melting Point ]:
>296ºC (dec.)

[ Molecular Formula ]:
C₁₄H₁₁N₄NaO₂S

[ Molecular Weight ]:
322.318

[ Flash Point ]:
287.1ºC

[ Exact Mass ]:
322.050049

[ PSA ]:
94.32000

[ LogP ]:
4.26810

[ Storage condition ]:
0-6°C

[ Water Solubility ]:
H2O: 50 mg/mL, clear to almost clear, dark yellow

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful;

[ Risk Phrases ]:
R22;R42/43

[ Safety Phrases ]:
S22-S36/37-S45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Development of a novel carbon paste sensor for determination of micromolar amounts of sulfaquinoxaline in pharmaceutical and biological samples.

Mater. Sci. Eng. C. Mater. Biol. Appl. 58 , 504-9, (2015)

A potentiometric carbon paste sensor was fabricated for determination of sulfaquinoxaline (SQX) based on the use of ion-association complex of sulfaquinoxaline sodium with 2,3,5-triphenyltetrazolium c...

A landmark contribution to poultry science--prophylactic control of coccidiosis in poultry.

Poult. Sci. 88 , 813-815, (2009)

"Continuous feeding of low concentrations of sulfaquinoxaline for the control of coccidiosis in poultry" by L. C. Grumbles, J. P. Delaplane, and T. C. Higgins [Poult. Sci. (1948) 27:605-608] was the f...

The effect of sulfaquinoxaline administration on metabolism of vitamin A and carotene and on hemoglobin young dairy calves.

J. Anim. Sci. 9 , 314-320, (1950)