5(6)-Carboxytetramethylrhodamine

Names

[ Name ]:
5(6)-Carboxytetramethylrhodamine

[Synonym ]:
5(6)-Carboxytetramethylrhodamine hydrochloride
2-[3,6-Bis(dimethylamino)-9-xantheniumyl]benzoate - (H)formic acid (1:1)
BIC1056
5(6)-Carboxytetramethylrhodamine
5(6)-TAMRA

Biological Activity

[Description]:

5(6)-TAMRA contains a carboxylic acid that can be used to react with primary amines via carbodiimide activation of the carboxylic acid; bright, orange-fluorescent dye produces conjugates with absorption/emission maxima of ~555/580 nm.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Dye Reagents

Research Areas >> Others

[References]

[1]. Fuchs SM, et al. Pathway for polyarginine entry into mammalian cells. Biochemistry. 2004 Mar 9;43(9):2438-44.

[2]. Gerber D, et al. Insertion and organization within membranes of the delta-endotoxin pore-forming domain, helix 4-loop-helix 5, and inhibition of its activity by a mutant helix 4 peptide. J Biol Chem. 2000 Aug 4;275(31):23602-7.

[3]. Vinayak R, et al. Automated, solid-phase coupling of rhodamine dye acids to 5' amino oligonucleotides. Nucleic Acids Symp Ser. 2000;(44):257-8.

[Related Small Molecules]

Chemical & Physical Properties

[ Melting Point ]:
≥300ºC(lit.)

[ Molecular Formula ]:
C₂₅H₂₂N₂O₅

[ Molecular Weight ]:
430.45

[ PSA ]:
194.10000

[ LogP ]:
9.05960

[ Storage condition ]:
-20℃

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi: Irritant;

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

Articles

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To investigate the suitability of three antimicrobial peptides (AMPs) as cell-penetrating antimicrobial peptides.Cellular uptake of three AMPs (PK-12-KKP, SA-3 and TPk) and a cell-penetrating peptide ...

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Macromol. Biosci. 15(1) , 52-62, (2015)

To address the downside of conventional photo-patterning which can alter the chemical composition of protein scaffolds, we developed a non-covalent photo-patterning strategy for gelatin (denatured col...