Defensin HNP-2 human

Names

[ Name ]:
Defensin HNP-2 human

[Synonym ]:
Human neutrophil peptide 2 (CYCRIPACIAGERRYGTCIYQGRLWAFCC)
Defensin HNP-2 human
HNP2
HNP-2, Defensin Human Neutrophil Peptide-2

Biological Activity

[Description]:

Defensin HNP-2 human is an endogenous antibiotic peptide and monocyte chemotactic peptide produced by human neutrophils.

[Target]

Human Endogenous Metabolite

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄₇H₂₁₇N₄₃O₃₇S₆

[ Molecular Weight ]:
3370.95000

[ Exact Mass ]:
3368.47000

[ PSA ]:
1445.83000

[ LogP ]:
6.15780

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Structure, function, and membrane integration of defensins.

Curr. Opin. Struct. Biol. 5 , 521-527, (1995)

Defensins comprise a structural class of small cationic peptides that exert broad-spectrum antimicrobial activities through membrane permeabilization. Their predominantly beta-sheet structure, stabili...

Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin.

Infect. Immun. 55 , 2281, (1987)

A broad-spectrum antimicrobial peptide present in guinea pig neutrophils was isolated, characterized biochemically, and assessed for microbicidal range and potency in vitro. The guinea pig neutrophil ...

Human β-defensin-2. Schroder J.M., and Harder, J.

Int. J. Biochem. Cell Biol. 31 , 645-651, (1998)