2',4',5,7-Tetrahydroxyisoflavone

Modify Date: 2024-01-03 12:01:10

2',4',5,7-Tetrahydroxyisoflavone Structure
2',4',5,7-Tetrahydroxyisoflavone structure
Common Name 2',4',5,7-Tetrahydroxyisoflavone
CAS Number 1156-78-1 Molecular Weight 286.24
Density 1.7±0.1 g/cm3 Boiling Point 619.1±55.0 °C at 760 mmHg
Molecular Formula C15H10O6 Melting Point N/A
MSDS N/A Flash Point 240.7±25.0 °C

 Use of 2',4',5,7-Tetrahydroxyisoflavone


2′-Hydroxygenistein is a natural product that can be isolated from Crotalaria pallida and C. assamica. 2′-Hydroxygenistein shows anti-inflammatory activity. 2′-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of β-glucuronidase and lysozyme from rat neutrophils, with IC50 values of 5.9 ± 1.4 and 9.7 ± 3.5 μM, respectively[1].

 Names

Name 2'-hydroxygenistein
Synonym More Synonyms

 2',4',5,7-Tetrahydroxyisoflavone Biological Activity

Description 2′-Hydroxygenistein is a natural product that can be isolated from Crotalaria pallida and C. assamica. 2′-Hydroxygenistein shows anti-inflammatory activity. 2′-Hydroxygenistein shows significant concentration-dependent inhibitory effects on the release of β-glucuronidase and lysozyme from rat neutrophils, with IC50 values of 5.9 ± 1.4 and 9.7 ± 3.5 μM, respectively[1].
Related Catalog
References

[1]. Ko HH, Weng JR, Tsao LT, Yen MH, Wang JP, Lin CN. Anti-inflammatory flavonoids and pterocarpanoid from Crotalaria pallida and C. assamica. Bioorg Med Chem Lett. 2004 Feb 23;14(4):1011-4.  

 Chemical & Physical Properties

Density 1.7±0.1 g/cm3
Boiling Point 619.1±55.0 °C at 760 mmHg
Molecular Formula C15H10O6
Molecular Weight 286.24
Flash Point 240.7±25.0 °C
Exact Mass 286.047729
PSA 111.13000
LogP 2.99
Vapour Pressure 0.0±1.9 mmHg at 25°C
Index of Refraction 1.768

 Safety Information

Hazard Codes Xi
HS Code 2914501900

 Synthetic Route

 Customs

HS Code 2914501900
Summary 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

 Synonyms

3-(2,4-dihydroxyphenyl)-5,7-dihydroxychromen-4-one
2',4',5,7-Tetrahydroxyisoflavone
Isoflavone, 2',4',5,7-tetrahydroxy-
2'-HYDROXYGENISTEIN
4H-1-Benzopyran-4-one, 3-(2,4-dihydroxyphenyl)-5,7-dihydroxy-
5,7,2',4'-Tetrahydroxy-isoflavone
3-(2,4-Dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4-one
MFCD00075967