Clomipramine-d3 (hydrochloride)

Modify Date: 2024-01-16 14:55:20

Clomipramine-d3 (hydrochloride) structure	Common Name	Clomipramine-d3 (hydrochloride)
	CAS Number	1398065-86-5	Molecular Weight	354.332
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₉H₂₁D₃Cl₂N₂	Melting Point	N/A
	MSDS	N/A	Flash Point	9℃
	Symbol	GHS02, GHS06, GHS08	Signal Word	Danger

Use of Clomipramine-d3 (hydrochloride)

Clomipramine D3 hydrochloride is a deuterium labeled Clomipramine hydrochloride. Clomipramine hydrochloride is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].

Name	Clomipramine D3 Hydrochloride
Synonym	More Synonyms

Description	Clomipramine D3 hydrochloride is a deuterium labeled Clomipramine hydrochloride. Clomipramine hydrochloride is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively[1][2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor Research Areas >> Neurological Disease Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter
References	[1]. Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283(3): p. 1305-22. [2]. McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39(1): p. 136-53.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor

Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor

Research Areas >> Neurological Disease

Signaling Pathways >> Neuronal Signaling >> Serotonin Transporter

References

[1]. Owens, M.J., et al., Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites. J Pharmacol Exp Ther, 1997. 283(3): p. 1305-22.

[2]. McTavish, D. and P. Benfield, Clomipramine. An overview of its pharmacological properties and a review of its therapeutic use in obsessive compulsive disorder and panic disorder. Drugs, 1990. 39(1): p. 136-53.

Molecular Formula	C₁₉H₂₁D₃Cl₂N₂
Molecular Weight	354.332
Flash Point	9℃
Exact Mass	353.150482
Storage condition	-20°C

Symbol	GHS02, GHS06, GHS08
Signal Word	Danger
Hazard Statements	H225-H301 + H311 + H331-H370
Precautionary Statements	P210-P260-P280-P301 + P310-P311
RIDADR	UN1230 - class 3 - PG 2 - Methanol, solution

3-(3-Chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N-methyl-N-(2H3)methyl-1-propanamine hydrochloride (1:1)

5H-Dibenz[b,f]azepine-5-propanamine, 3-chloro-10,11-dihydro-N-methyl-N-(methyl-d3)-, hydrochloride (1:1)

Clomipramine-d3 (hydrochloride)

Use of Clomipramine-d3 (hydrochloride)

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Clomipramine-d3 (hydrochloride) Biological Activity

Chemical & Physical Properties

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