喷他佐辛
喷他佐辛结构式
|
常用名 | 喷他佐辛 | 英文名 | (R)-Pentazocine |
|---|---|---|---|---|
| CAS号 | 359-83-1 | 分子量 | 285.424 | |
| 密度 | 1.0±0.1 g/cm3 | 沸点 | 403.5±45.0 °C at 760 mmHg | |
| 分子式 | C19H27NO | 熔点 | 145.4-147.20ºC | |
| MSDS | 中文版 美版 | 闪点 | 180.8±27.4 °C | |
| 符号 |
GHS07 |
信号词 | Warning |
| 中文名 | 喷他佐辛 |
|---|---|
| 英文名 | 6-(2-Fluorophenyl)picolinimidamidehydrochloride |
| 英文别名 | 更多 |
| 密度 | 1.0±0.1 g/cm3 |
|---|---|
| 沸点 | 403.5±45.0 °C at 760 mmHg |
| 熔点 | 145.4-147.20ºC |
| 分子式 | C19H27NO |
| 分子量 | 285.424 |
| 闪点 | 180.8±27.4 °C |
| 精确质量 | 285.209259 |
| PSA | 23.47000 |
| LogP | 4.53 |
| 外观性状 | 结晶固体 |
| 蒸汽压 | 0.0±1.0 mmHg at 25°C |
| 折射率 | 1.554 |
| 储存条件 | Controlled Substance, -20?C Freezer |
| 水溶解性 | DMSO: >10mg/mL |
| 符号 |
GHS07 |
|---|---|
| 信号词 | Warning |
| 危害声明 | H302 |
| 警示性声明 | P301 + P312 + P330 |
| 个人防护装备 | dust mask type N95 (US);Eyeshields;Gloves |
| 危害码 (欧洲) | Xn: Harmful; |
| 风险声明 (欧洲) | R22 |
| 安全声明 (欧洲) | 7-16-36/37-45 |
| 危险品运输编码 | UN1230 - class 3 - PG 2 - Methanol, solution |
| RTECS号 | PB8750000 |
|
~94%
喷他佐辛 359-83-1 |
| 文献：Chen, Qiang; Huo, Xing; Yang, Zhen; She, Xuegong Chemistry - An Asian Journal, 2012 , vol. 7, # 11 p. 2543 - 2546,4 |
|
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喷他佐辛 359-83-1 |
| 文献：Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745 |
|
~%
喷他佐辛 359-83-1 |
| 文献：Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745 |
|
~%
喷他佐辛 359-83-1 |
| 文献：Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745 |
|
~%
喷他佐辛 359-83-1 |
| 文献：Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745 |
|
~%
喷他佐辛 359-83-1 |
| 文献：Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745 |
|
~%
喷他佐辛 359-83-1 |
| 文献：Journal of the American Chemical Society, , vol. 125, # 29 p. 8744 - 8745 |
|
~%
喷他佐辛 359-83-1 |
| 文献：Chemistry - An Asian Journal, , vol. 7, # 11 p. 2543 - 2546,4 |
|
Allosteric modulation of sigma-1 receptors elicits anti-seizure activities.
Br. J. Pharmacol. 172 , 4052-65, (2015) Application of orthosteric sigma-1 receptor agonists as anti-seizure drugs has been hindered by questionable efficacy and potential adverse effects. Here, we have investigated the anti-seizure effects... |
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Involvement of hypothalamic neuropeptide Y in pentazocine induced suppression of food intake in rats.
Neuropeptides 48(3) , 133-41, (2014) The potent orexigenic peptide neuropeptide Y (NPY) has been considered as a possible endogenous ligand for a subpopulation of sigma receptors (SigR). However, their mutual interaction with reference t... |
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Synthesis and biological evaluation of novel sigma-1 receptor antagonists based on pyrimidine scaffold as agents for treating neuropathic pain.
J. Med. Chem. 57(24) , 10404-23, (2014) The discovery and synthesis of a new series of pyrimidines as potent sigma-1 receptor (σ1R) antagonists, associated with pharmacological antineuropathic pain activity, are the focus of this article. T... |
| Sosigon |
| UNII:RP4A60D26L |
| (1R,9R,13R)-1,13-Dimethyl-10-(3-methylbut-2-en-1-yl)-10-azatricyclo[7.3.1.0]trideca-2,4,6-trien-4-ol |
| Fortalin |
| α-(−)-Pentazocine |
| Fortral |
| Sosegon |
| (1R,9R,13R)-1,13-diméthyl-10-(3-méthylbut-2-én-1-yl)-10-azatricyclo[7.3.1.0]tridéca-2,4,6-trién-4-ol |
| 2,6-methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-, (2R,6R,11R)- |
| 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-buten-1-yl)-, (2R,6R,11R)- |
| II-C-2 |
| cis-(−)-pentazocine |
| PENTAZOCINE |
| 2-Dimethylallyl-5,9-dimethyl-2'-hydroxybenzomorphan |
| (2R,6R,11R)-6,11-dimethyl-3-(3-methylbut-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol |
| Pentagin |
