丙酮缩甘油
丙酮缩甘油用途
鲨肝醇的中间体。万能溶剂、增塑剂、药用辅料(助溶剂、悬浮剂)。
丙酮缩甘油名称
[ CAS 号 ]:
100-79-8
[ 中文名 ]:
丙酮缩甘油
[ 英文名 ]:
Solketal
[中文别名 ]:
[英文别名 ]:
- (±)-2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane
- Solketal
- (2,2-Dimethyl-1,3-dioxolan-4-yl)methanol
- 2,3-(Isopropylidenedioxy)propanol
- (±)-2,2-Dimethyl-1,3-dioxolane-4-methanol
- 1,2-Isopropylidene-rac-glycerol
- (RS)-Solketal
- 2,2-Dimethyl-4-hydroxymethyl-1,3-dioxolane
- 1,2-Isopropylideneglycerol
- T5O COTJ B1 B1 D1Q
丙酮缩甘油物理化学性质
[ 密度 ]:
1.0±0.1 g/cm3
[ 沸点 ]:
188.5±0.0 °C at 760 mmHg
[ 分子式 ]:
C6H12O3
[ 分子量 ]:
132.158
[ 闪点 ]:
80.0±0.0 °C
[ 精确质量 ]:
132.078644
[ PSA ]:
38.69000
[ LogP ]:
0.06
[ 外观性状 ]:
透明无色液体
[ 蒸汽压 ]:
0.2±0.7 mmHg at 25°C
[ 折射率 ]:
1.424
[ 储存条件 ]:
2-8°C
[ 水溶解性 ]:
miscible
丙酮缩甘油MSDS
丙酮缩甘油毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- JI0400000
- CHEMICAL NAME :
- 1,3-Dioxolane-4-methanol, 2,2-dimethyl-
- CAS REGISTRY NUMBER :
- 100-79-8
- BEILSTEIN REFERENCE NO. :
- 0104465
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C6-H12-O3
- MOLECULAR WEIGHT :
- 132.18
- WISWESSER LINE NOTATION :
- T5O COTJ B1 B1 D1Q
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3740 ug/kg
- TOXIC EFFECTS :
- Cardiac - change in rate Vascular - BP elevation not characterized in autonomic section Vascular - BP lowering not characterized in autonomic section
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 8530 ug/kg
- TOXIC EFFECTS :
- Cardiac - change in rate Vascular - BP elevation not characterized in autonomic section Vascular - BP lowering not characterized in autonomic section
MUTATION DATA
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 1500 mg/kg
- REFERENCE :
- TOLED5 Toxicology Letters. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1977- Volume(issue)/page/year: 21,349,1984
丙酮缩甘油安全信息
[ 符号 ]:
GHS07
[ 信号词 ]:
Warning
[ 危害声明 ]:
H319
[ 警示性声明 ]:
P305 + P351 + P338
[ 个人防护装备 ]:
Eyeshields;Gloves;half-mask respirator (US);multi-purpose combination respirator cartridge (US)
[ 危害码 (欧洲) ]:
Xi: Irritant;
[ 风险声明 (欧洲) ]:
R36/37/38
[ 安全声明 (欧洲) ]:
S24/25
[ WGK德国 ]:
2
[ RTECS号 ]:
JI0400000
[ 海关编码 ]:
29329970
丙酮缩甘油合成路线
丙酮缩甘油上下游产品
丙酮缩甘油上游产品
丙酮缩甘油下游产品
丙酮缩甘油制备
用丙三醇与丙酮在氰化氢作用下缩合制得。
丙酮缩甘油海关
[ 海关编码 ]: 2932999099
[ 中文概述 ]:
2932999099. 其他仅含氧杂原子的杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途
[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
丙酮缩甘油文献
BMC Plant Biol. 10 , 114, (2010)
Recent discoveries highlighting the metabolic malleability of plant lignification indicate that lignin can be engineered to dramatically alter its composition and properties. Current plant biotechnolo...
In vitro toxicities of experimental jet fuel system ice-inhibiting agents.Sci. Total Environ. 274(1-3) , 209-18, (2001)
One research emphasis within the Department of Defense has been to seek the replacement of operational compounds with alternatives that pose less potential risk to human and ecological systems. Altern...
Effects of glycerol acetonide on adrenergic neurotransmission in isolated rabbit heart.Arzneimittelforschung 42(11) , 1288-91, (1992)
In the present investigation, the solvent glycerol acetonide (GA, CAS 100-79-8) was added (110 mg/min) to the Tyrode buffer perfusing an isolated rabbit heart preloaded with 14C-noradrenaline (NA). GA...
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相关化合物
【丙酮缩甘油】化源网提供丙酮缩甘油CAS号100-79-8,丙酮缩甘油MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询丙酮缩甘油上化源网,专业又轻松。>>电脑版:丙酮缩甘油
标题:丙酮缩甘油_MSDS_用途_密度_丙酮缩甘油CAS号【100-79-8】_化源网 地址:https://www.chemsrc.com/amp/cas/100-79-8_448641.html