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五丙氨酸

五丙氨酸用途

Penta-alanine (Penta-L-alanine) 是一种肽。Penta-alanine 可用于神经系统疾病研究。

五丙氨酸名称

[ CAS 号 ]:
10183-34-3

[ 中文名 ]:
五丙氨酸

[ 英文名 ]:
H-Ala-Ala-Ala-Ala-Ala-OH

[英文别名 ]:

D-Penta-L-Alanine
L-alanyl-L-alanyl-L-alanyl-L-alanyl-L-alanine
Ala-(Ala)3-Ala
ALA-ALA-ALA-ALA-ALA
PENTA-ALA
PENTA-L-ALANINE
L-ALA-ALA-ALA-ALA-ALA

五丙氨酸生物活性

[ 描述 ]:

Penta-alanine (Penta-L-alanine) 是一种肽。Penta-alanine 可用于神经系统疾病研究。

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 神经疾病

[参考文献]

[1]. Niu L, et al. Transformation of β-sheet structures of the amyloid peptide induced by molecular modulators. Chem Commun (Camb). 2014 Aug 18;50(64):8923-6.

[2]. Mu Y, et al. Energy landscape of a small peptide revealed by dihedral angle principal component analysis. Proteins. 2005 Jan 1;58(1):45-52.

五丙氨酸物理化学性质

[ 分子式 ]:
C₁₅H₂₇N₅O₆

[ 分子量 ]:
373.40500

[ 精确质量 ]:
373.19600

[ PSA ]:
179.72000

[ 储存条件 ]:
2-8°C，密封，干燥

五丙氨酸MSDS

详细MSDS(安全技术说明书)

五丙氨酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

五丙氨酸文献

Protein dynamical transition does not require protein structure.

Phys. Rev. Lett. 101 , 178103, (2008)

Terahertz time domain spectroscopy shows that the protein dynamical transition, the rapid increase in protein dynamics occurring at approximately 200 K, needs neither tertiary nor secondary structure....

Using J-coupling constants for force field validation: application to hepta-alanine.

J. Phys. Chem. B 115 , 15221-15227, (2011)

A computational solution to the protein folding problem is the holy grail of biomolecular simulation and of the corresponding force fields. The complexity of the systems used for folding simulations p...

Resampling improves the efficiency of a "fast-switch" equilibrium sampling protocol.

J. Chem. Phys. 130 , 081102, (2009)

We recently applied a multistage reweighting scheme to demonstrate the sampling of equilibrium configurational distributions of peptides from nonequilibrium, simulated annealing trajectories [E. Lyman...

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