<生产厂家价格>

肉桂酸苄酯

肉桂酸苄酯用途

Benzyl cinnamate,存在于秘鲁香脂和托鲁香脂中,存在于苏门答腊和槟城的苯甲酸中,可用作香水和固定剂的成分。

肉桂酸苄酯名称

[ CAS 号 ]:
103-41-3

[ 中文名 ]:
肉桂酸苄酯

[ 英文名 ]:
Benzyl cinnamate

[中文别名 ]:

桂酸苄酯

[英文别名 ]:

Cinnamic Acid Benzyl Ester
benzyl trans-3-phenylpropenoate
FEMA 2142
Benzyl (2E)-3-phenyl-2-propenoate
benzyl (2E)-3-phenylprop-2-enoate
Benzyl Alcohol Cinnamate
Benzyl cinnamate
Benzyl γ-phenylacrylate
EINECS 203-109-3
Benzyl ciamate

肉桂酸苄酯生物活性

[ 描述 ]:

Benzyl cinnamate,存在于秘鲁香脂和托鲁香脂中,存在于苏门答腊和槟城的苯甲酸中,可用作香水和固定剂的成分。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 其他 >> 其他

[参考文献]

[1]. Bhatia SP, et al. Fragrance material review on benzyl cinnamate. Food Chem Toxicol. 2007;45 Suppl 1:S40-8. Epub 2007 Sep 14.

肉桂酸苄酯物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
195-200 ºC (5 mmHg)

[ 熔点 ]:
34-37 °C(lit.)

[ 分子式 ]:
C₁₆H₁₄O₂

[ 分子量 ]:
238.281

[ 闪点 ]:
225.7±10.4 °C

[ 精确质量 ]:
238.099380

[ PSA ]:
26.30000

[ LogP ]:
3.65

[ 外观性状 ]:
白色至淡黄色晶体

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.4025-1.4045

[ 储存条件 ]:
通风低温干燥

[ 水溶解性 ]:
PRACTICALLY INSOLUBLE

肉桂酸苄酯MSDS

肉桂酸苄酯毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: GD8400000

CHEMICAL NAME :: Cinnamic acid, benzyl ester

CAS REGISTRY NUMBER :: 103-41-3

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C16-H14-O2

MOLECULAR WEIGHT :: 238.30

WISWESSER LINE NOTATION :: R1U1VO1R

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,1017,1973 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 5530 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - coma

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 2,327,1964

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 3760 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - gastritis

REFERENCE :: FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 2,327,1964 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83174 No. of Facilities: 21 (estimated) No. of Industries: 1 No. of Occupations: 2 No. of Employees: 456 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83174 No. of Facilities: 546 (estimated) No. of Industries: 3 No. of Occupations: 6 No. of Employees: 2855 (estimated) No. of Female Employees: 1107 (estimated)

肉桂酸苄酯安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
3077

[ WGK德国 ]:
2

[ RTECS号 ]:
GD8400000

[ 海关编码 ]:
29163900

肉桂酸苄酯合成路线

肉桂酸苄酯上下游产品

肉桂酸苄酯上游产品

肉桂酸苄酯下游产品

肉桂酸苄酯制备

1.主要采用配化法和缩合法。酯化法是以肉桂酸为原料先与氢氧化钠进行中和，然后与氯代甲苯进行酯化反应而得。缩合法是以乙酸苄酯和苯甲醛为原料，经缩合反应而得。

2.采用天然物提取法和肉桂酸合成法。天然物提取法是将存在于秘鲁香脂、吐鲁香脂及安息香中的肉桂酸苄酯用提取法抽提而得。肉桂酸合成法是以肉桂酸为原料，先用氢氧化钠溶液中和，然后与氯代甲苯进行酯化反应，最后经精制而得。

3. 桂酸和苄醇直接酯化法：使用苄醇和桂酸甲酯进行酯交换的方法：桂酸钠和氯化苄相互作用的方法：由乙酸苄酯和苯甲酸进行Claisen缩合的方法。

肉桂酸苄酯海关

[ 海关编码 ]: 29163900

肉桂酸苄酯文献

Novel natural product-based cinnamates and their thio and thiono analogs as potent inhibitors of cell adhesion molecules on human endothelial cells.

Eur. J. Med. Chem. 46 , 5498-511, (2011)

In the present study, we report the design and synthesis of novel analogs of cinnamates, thiocinnamates and thionocinnamates and evaluated the potencies of these analogs to inhibit TNF-α induced ICAM-...

Determination of UV filters and antimicrobial agents in environmental water samples.

Anal. Bioanal. Chem 387(4) , 1343-50, (2007)

Although there is increasing concern about residues from personal care products entering the aquatic environment and their potential to accumulate to levels that pose a health threat to humans and wil...

Study on the constituents of Mexican propolis and their cytotoxic activity against PANC-1 human pancreatic cancer cells.

J. Nat. Prod. 73 , 623-7, (2010)

Three new flavonoids, (2R,3R)-3,5-dihydroxy-7-methoxyflavanone 3-(2-methyl)butyrate (1), (7''R)-8-[1-(4'-hydroxy-3'-methoxyphenyl)prop-2-en-1-yl]chrysin (2), and (7''R)-8-[1-(4'-hydroxy-3'-methoxyphen...

更多文献