异丁酰基辅酶 A

异丁酰基辅酶 A用途

异丁酰辅酶A锂盐(Quin 2,四钾盐)是辅酶A的一种。辅酶A作为酰基载体,即乙酰辅酶A。异丁酰基辅酶a(IB-CoA)是一种短链支链酰基辅酶a,为myxalamid B生物合成提供起始单元。以异丁酰辅酶a为底物,研究了异丁酰CoA(CoA)突变酶(EC 5.4.99.13)的特异性和动力学。

异丁酰基辅酶 A名称

[ CAS 号 ]:
103404-95-1

[ 中文名 ]:
异丁酰基辅酶A锂盐

[ 英文名 ]:
Isobutyryl coenzyme A lithium salt

[英文别名 ]:

异丁酰基辅酶 A生物活性

[ 描述 ]:

[ 相关类别 ]:

研究领域 >> 其他

异丁酰基辅酶 A物理化学性质

[ 分子式 ]:
C₂₅H₄₂LiN₇O₁₇P₃S

[ 分子量 ]:
844.56500

[ 精确质量 ]:
844.17300

[ PSA ]:
425.34000

[ LogP ]:
1.58250

[ 外观性状 ]:
固体

[ 储存条件 ]:
20°C

异丁酰基辅酶 AMSDS

详细MSDS(安全技术说明书)

异丁酰基辅酶 A安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

异丁酰基辅酶 A文献

Cloning and sequencing of the coenzyme B(12)-binding domain of isobutyryl-CoA mutase from Streptomyces cinnamonensis, reconstitution of mutase activity, and characterization of the recombinant enzyme produced in Escherichia coli.

J. Biol. Chem. 274 , 31679-31685, (1999)

Isobutyryl-CoA mutase (ICM) catalyzes the reversible, coenzyme B(12)-dependent rearrangement of isobutyryl-CoA to n-butyryl-CoA, which is similar to, but distinct from, that catalyzed by methylmalonyl...

Enhanced production of ansamitocin P-3 by addition of isobutanol in fermentation of Actinosynnema pretiosum.

Bioresour. Technol. 102 , 1863-1868, (2011)

Supply of isobutanol to enhance the production of anti-tumor agent ansamitocin P-3 (AP-3) in medium containing agro-industrial residues was investigated with analysis of gene transcription, enzyme act...

Mutasynthesis-derived myxalamids and origin of the isobutyryl-CoA starter unit of myxalamid B.

ChemBioChem. 8 , 2139-2144, (2007)

Myxalamids are potent inhibitors of the eukaryotic electron transport chain produced by different myxobacteria. Here, we describe the identification of the myxalamid biosynthesis gene cluster from Myx...

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