溴代丙炔

溴代丙炔用途

【用途一】
用于有机合成
【用途二】
溴丙炔是拟除虫菊酯丙炔菊酯的中间体。
【用途三】
用于合成乙炔各种衍生物；医药工业用于制造抗霉菌药氯丙炔碘。
【用途四】
用于合成乙炔各种衍生物；医药工业用于制造抗霉菌药氯丙炔碘。用于制造丙炔胺（烯炔替代）。

溴代丙炔名称

[ CAS 号 ]:
106-96-7

[ 中文名 ]:
3-溴丙炔

[ 英文名 ]:
3-Bromopropyne

[中文别名 ]:

[英文别名 ]:

1-Propyne, 3-bromo-
3-Bromopropyne [UN2345] [Flammable liquid]
EINECS 203-447-1
3-Bromopropyne
Propargyl Bromide
4-01-00-00964 (Beilstein Handbook Reference)
Propyne, 3-bromo-
γ-Bromoallylene
3-bromoprop-1-yne
3-Bromo-1-propyne

溴代丙炔物理化学性质

[ 密度 ]:
1.6±0.1 g/cm3

[ 沸点 ]:
90.0±13.0 °C at 760 mmHg

[ 熔点 ]:
-61°C

[ 分子式 ]:
C₃H₃Br

[ 分子量 ]:
118.960

[ 闪点 ]:
17.1±14.3 °C

[ 精确质量 ]:
117.941803

[ LogP ]:
1.32

[ 外观性状 ]:
透明至黄色液体

[ 蒸汽压 ]:
64.6±0.2 mmHg at 25°C

[ 折射率 ]:
1.485

[ 储存条件 ]:
库房通风低温干燥,与氧化剂分开储运存放

[ 水溶解性 ]:
水溶性：不溶；可溶于：乙醇,苯,乙醚

溴代丙炔MSDS

溴代丙炔毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UK4375000

CHEMICAL NAME :: Propyne, 3-bromo-

CAS REGISTRY NUMBER :: 106-96-7

BEILSTEIN REFERENCE NO. :: 0605309

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C3-H3-Br

MOLECULAR WEIGHT :: 118.97

WISWESSER LINE NOTATION :: E2UU1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 53 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BESAAT Bulletin of the Entomological Society of America. (Entomological Soc. of America, 4603 Calvert Rd., College Park, MD 20740) V.1- 1955- Volume(issue)/page/year: 12,161,1966

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 29 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 28ZEAL "Pesticide Index," Frear, E.H., ed., State College, PA, College Science Pub., 1969 Volume(issue)/page/year: 4,76,1969 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X7175 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)

溴代丙炔安全信息

[ 符号 ]:

GHS02, GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H225-H301-H304-H315-H319-H335-H336-H361d-H373

[ 警示性声明 ]:
P210-P261-P281-P301 + P310-P305 + P351 + P338-P331

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
F:Flammable;T:Toxic;

[ 风险声明 (欧洲) ]:
R11;R25;R36/37/38;R63

[ 安全声明 (欧洲) ]:
S53-S16-S36/37/39-S45-S37/39-S28A-S26-S62

[ 危险品运输编码 ]:
UN 2345 3/PG 2

[ WGK德国 ]:
3

[ RTECS号 ]:
UK4375000

[ 包装等级 ]:
II

[ 危险类别 ]:
3

[ 海关编码 ]:
2903399090

溴代丙炔合成路线

溴代丙炔上下游产品

溴代丙炔上游产品

溴代丙炔下游产品

溴代丙炔制备

1.由炔丙醇与溴化磷反应而得。将炔丙醇在冷却下加入吡啶，搅拌于-5℃缓缓滴加三溴化磷，反应温度维持在0℃以下。加毕，继续搅拌15min。然后，减压蒸馏，收集全部馏出液，在常压下再分馏一次，得成品。其制备方法是在反应瓶内加入溴化氢和溶剂，在CuBr及Cu催化剂存在下，在搅拌情况下滴加炔丙醇，滴完后略升温反应，然后后处理，精馏得溴丙炔。或用炔丙醇与(PhO) ₃PBr ₂在吡啶存在下反应也能得到产品。
或在干燥的炔丙醇中加入少量吡啶，在搅拌情况下于0℃滴加三溴化磷与少量的吡啶溶液，滴完后再搅拌20min，减压蒸馏得产品。 2.制法：

于装有搅拌器、温度计、回流冷凝器、滴液漏斗的反应瓶中，加入炔丙醇(2)112g（2.0mol），搅拌下冰盐浴冷至0℃以下，慢慢加入吡啶^①18g，冷至-5℃以下，滴加三溴化磷200g(0.74mol),控制滴加温度不超过0℃，约1.5h加完，而后继续搅拌反应0.5h。水泵减压蒸馏，收集全部馏出物，再常压分馏，收集83～89℃的馏分，得炔丙基溴(1)180g,收率76%。注：①加入过程中放热，注意不要一次加入，以免温度上升。

溴代丙炔海关

[ 海关编码 ]: 2903399090

[ 中文概述 ]:
2903399090. 其他无环烃的氟化、溴化或碘化衍生物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:5.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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