二异丙醇胺

二异丙醇胺用途

【用途一】
用于天然气及炼厂气中脱除硫化氢和二氧化碳，用于纤维助剂、鞣革剂、杀虫剂、切削油等
【用途二】
二异丙醇胺用作酸性气体的吸收剂，例如用来吸收天然气及石油炼制气中的CO2，H2S，合成氨工业中去除合成气中的CO2，干冰生产中用来浓缩CO2。另外还用于金属退火、惰性气体制造、电泳涂料的中和剂等。该品在乳化剂方面，应用于纤维助剂、鞣革剂、杀虫剂、切削油、涂料及蜡制品。二异丙醇胺与脂肪酸反应生成脂肪酸酰胺和脂，用作洗发剂的活性组分。
【用途三】
二异丙醇胺用作酸性气体的吸收剂，例如用来吸收天然气及石油炼制气中的CO2，H2S，合成氨工业中去除合成气中的CO2，干冰生产中用来浓缩CO2。另外还用于金属退火、惰性气体制造、电泳涂料的中和剂等。

二异丙醇胺名称

[ CAS 号 ]:
110-97-4

[ 中文名 ]:
二异丙醇胺

[ 英文名 ]:
UNII:0W44HYL8T5

[中文别名 ]:

[英文别名 ]:

DIPROPYL-2,2'-DIHYDROXYAMINE
1,1'-Iminodi(2-propanol)
diisopropanolamine
DIPA commercial grade
2-Propanol, 1,1'-iminobis-
1,1'-Imino-2-propanol
1,1'-Iminodipropan-2-ol
IMINODIPROPANOL
EINECS 203-820-9
UNII:0W44HYL8T5

二异丙醇胺物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
254.4±15.0 °C at 760 mmHg

[ 熔点 ]:
42-45 °C(lit.)

[ 分子式 ]:
C₆H₁₅NO₂

[ 分子量 ]:
133.189

[ 闪点 ]:
126.7±0.0 °C

[ 精确质量 ]:
133.110275

[ PSA ]:
52.49000

[ LogP ]:
-0.81

[ 外观性状 ]:
透明至黄色固体

[ 蒸汽压 ]:
0.0±1.1 mmHg at 25°C

[ 折射率 ]:
1.463

[ 储存条件 ]:
库房通风低温干燥,与酸类分开存放

[ 水溶解性 ]:
870 G/L (20 ºC)

二异丙醇胺MSDS

详细MSDS(安全技术说明书)

二异丙醇胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB6600000

CHEMICAL NAME :: 2-Propanol, 1,1'-iminodi-

CAS REGISTRY NUMBER :: 110-97-4

BEILSTEIN REFERENCE NO. :: 0605363

LAST UPDATED :: 199710

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C6-H15-N-O2

MOLECULAR WEIGHT :: 133.22

WISWESSER LINE NOTATION :: QY1&1M1YQ1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 5/21/1971

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 5/21/1971 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4765 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(7),46,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 96 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - beta-adrenergic blockage

REFERENCE :: AIMJA9 Ain Shams Medical Journal. (Ain Shams Clinical and Scientific Soc., c/o Ain Shams Univ. Hospital, Abbassia, Cairo, Egypt) V.1- 1950- Volume(issue)/page/year: 30,23,1979

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(7),46,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 42 gm/kg/2W-C

TOXIC EFFECTS :: Musculoskeletal - other changes Related to Chronic Data - death

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(1),53,1987 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 1 mg/m3;Skin JAN 1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1242 No. of Facilities: 6081 (estimated) No. of Industries: 34 No. of Occupations: 44 No. of Employees: 73790 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1242 No. of Facilities: 1278 (estimated) No. of Industries: 26 No. of Occupations: 43 No. of Employees: 35237 (estimated) No. of Female Employees: 3439 (estimated)

二异丙醇胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319

[ 警示性声明 ]:
P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36

[ 安全声明 (欧洲) ]:
S26

[ 危险品运输编码 ]:
3259

[ WGK德国 ]:
1

[ RTECS号 ]:
UB6600000

[ 包装等级 ]:
III

[ 危险类别 ]:
8

[ 海关编码 ]:
2922199090

二异丙醇胺合成路线

详细合成路线

二异丙醇胺上下游产品

二异丙醇胺上游产品

二异丙醇胺下游产品

二异丙醇胺制备

由环氧丙烷与氨反应，生成一异丙醇胺，继续与环氧丙烷反应生成二、三异丙醇胺。环氧丙烷和氨混合后预热到反应温度，进入反应器反应。反应产物先经汽提，将氨和水除去，氨循环使用。然后，将粗异丙醇胺送至真空精馏系统，将一异丙醇胺、二异丙醇胺及三异丙醇胺分馏为纯产品。当原料配比中环氧丙烷过量较多时，所得产品中三异丙醇胺所占的比例增加。

二异丙醇胺海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

二异丙醇胺文献

Effect of diisopropanolamine upon choline uptake and phospholipid synthesis in Chinese hamster ovary cells.

Food Chem. Toxicol. 46(2) , 761-6, (2008)

Aminoalcohols differ in mammalian toxicity at least in part based upon their ability to alter the metabolism of phospholipids and to cause depletion of the essential nutrient choline in animals. This ...

Low expression of spindle checkpoint protein, Cenp-E, causes numerical chromosomal abnormalities in HepG-2 human hepatoma cells.

Oncol. Lett. 10 , 2699-2704, (2016)

The aim of the present study was to investigate the expression, localization and role of centromere-associated protein E (Cenp-E) in hepatoma cells. The Cenp-E mRNA expression levels in the HepG-2 hum...

Triple allergic contact sensitivities due to ferbinac, crotamiton and diisopropanolamine.

Contact Dermatitis 49(5) , 261-3, (2003)

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