硬脂醇

硬脂醇用途

Stearyl alcohol (also known as octadecyl alcohol or 1-octadecanol) is an organic compound classified as a fatty alcohol with the formula CH3(CH2)16CH2OH. It takes the form of white granules or flakes, which are insoluble in water. It has a wide range of uses as an ingredient in lubricants, resins, perfumes, and cosmetics. It is used as an emollient, emulsifier, and thickener in ointments.

硬脂醇名称

[ CAS 号 ]:
112-92-5

[ 中文名 ]:
硬脂醇

[ 英文名 ]:
Octadecanol

[中文别名 ]:

[英文别名 ]:

Octadecan-1-ol
Stearyl alcohol
MFCD00002823
octadecyl alcohol
steryl alcohol
stenol
1-Octadecanol
1-Hydroxyoctadecane
EINECS 204-017-6
Octadecanol

硬脂醇物理化学性质

[ 密度 ]:
0.812

[ 沸点 ]:
336 ºC

[ 熔点 ]:
56-59 °C(lit.)

[ 分子式 ]:
C₁₈H₃₈O

[ 分子量 ]:
270.494

[ 闪点 ]:
185 ºC

[ 精确质量 ]:
270.292267

[ PSA ]:
20.23000

[ LogP ]:
8.31

[ 外观性状 ]:
白色片状

[ 蒸汽密度 ]:
9.3 (vs air)

[ 蒸汽压 ]:
0.0±1.6 mmHg at 25°C

[ 折射率 ]:
1.451

[ 储存条件 ]:
库房通风低温干燥

[ 水溶解性 ]:
insoluble

硬脂醇MSDS

详细MSDS(安全技术说明书)

硬脂醇毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: RG2010000

CHEMICAL NAME :: 1-Octadecanol

CAS REGISTRY NUMBER :: 112-92-5

BEILSTEIN REFERENCE NO. :: 1362907

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C18-H38-O

MOLECULAR WEIGHT :: 270.56

WISWESSER LINE NOTATION :: Q18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(5),1,1985

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 4(5),1,1985 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 20 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 37ASAA "Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson, M., and D. Eckroth, eds., New York, John Wiley & Sons, Inc., 1978 Volume(issue)/page/year: 1,722,1978 ** TUMORIGENIC DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Implant

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1000 mg/kg

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Kidney, Ureter, Bladder - tumors

REFERENCE :: CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 26,105,1966 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80705 No. of Facilities: 3948 (estimated) No. of Industries: 37 No. of Occupations: 44 No. of Employees: 60590 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80705 No. of Facilities: 22262 (estimated) No. of Industries: 177 No. of Occupations: 127 No. of Employees: 508141 (estimated) No. of Female Employees: 181509 (estimated)

硬脂醇安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
UN 1986

[ WGK德国 ]:
-

[ RTECS号 ]:
RG2010000

[ 包装等级 ]:
I; II; III

[ 海关编码 ]:
2905170000

硬脂醇合成路线

详细合成路线

硬脂醇上下游产品

硬脂醇上游产品

硬脂醇下游产品

硬脂醇制备

1.可由巨头鲸油水解制得，也可在铬酸铜催化下由硬脂酸加氢而得，或用饱和乙醇还原硬脂酸乙酯。还可在烷基铝的作用下，通过控制乙烯的聚合反应得到十七烯馏分，再经羰基合成制得十八醇。

为制备色谱纯正十八醇，可以氮气为载气，在装有SE30／白色硅烷化硅藻土担体固定相柱的制备气相色谱仪上注入其粗品，经分离收集其主峰组分，然后密封保存即可。

硬脂醇海关

[ 海关编码 ]: 2905170000

[ 中文概述 ]:
2905170000 十二醇、十六醇及十八醇。监管条件:无。增值税率:17.0%。退税率:9.0%。最低关税:7.0%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ Summary ]:
2905170000 hexadecan-1-ol。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。Lowest tariff:7.0%。General tariff:30.0%

硬脂醇文献

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硬脂醇