三异丙醇胺

三异丙醇胺用途

用途一:用作医药原料、照像显影液溶剂，人造纤维中作石蜡油的溶剂，化妆品的乳化剂等。
用途二:主要用于中间体的合成，以及用于PU上作为扩链剂和日化上用作中和剂等。
用途三:本品可用于气体吸收剂、抗氧剂；水泥行业作助磨剂；纤维工业用作精炼剂、抗静电剂、染色助剂、纤维润湿剂；在润滑油和切削油中用作抗氧剂、增塑剂；塑料行业作交联剂；也可用作钛白粉、矿物质的分散剂以及聚氨酯行业中的熟化剂等。

三异丙醇胺名称

[ CAS 号 ]:
122-20-3

[ 中文名 ]:
三异丙醇胺

[ 英文名 ]:
Triisopropanolamine

[中文别名 ]:

[英文别名 ]:

Nitrilotripropanol
1,1',1''-Nitrilotripropan-2-ol
1,1',1''-Nitrilotri(2-propanol)
UNII:W9EN9DLM98
Triisopropanolamine
2-Propanol, 1,1',1''-nitrilotris-
EINECS 204-528-4
MFCD00004533
1,1',1''-Nitrilotris-2-propanol
1-[bis(2-hydroxypropyl)amino]propan-2-ol

三异丙醇胺物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
296.4±0.0 °C at 760 mmHg

[ 熔点 ]:
48-52 °C(lit.)

[ 分子式 ]:
C₉H₂₁NO₃

[ 分子量 ]:
191.268

[ 闪点 ]:
167.0±21.0 °C

[ 精确质量 ]:
191.152145

[ PSA ]:
63.93000

[ LogP ]:
-0.07

[ 外观性状 ]:
透明至淡黄色液体

[ 蒸汽压 ]:
0.0±1.4 mmHg at 25°C

[ 折射率 ]:
1.495

[ 储存条件 ]:
室温

[ 水溶解性 ]:
可溶

[ 凝固点 ]:
52℃

三异丙醇胺MSDS

三异丙醇胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UB8750000

CHEMICAL NAME :: 2-Propanol, 1,1',1''-nitrilotri-

CAS REGISTRY NUMBER :: 122-20-3

BEILSTEIN REFERENCE NO. :: 1071570

LAST UPDATED :: 199710

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C9-H21-N-O3

MOLECULAR WEIGHT :: 191.31

WISWESSER LINE NOTATION :: QY1&1N1YQ1&1YQ1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AJOPAA American Journal of Ophthalmology. (Ophthalmic Pub. Co., 435 N. Michigan Ave., Suite 1415, Chicago, IL 60611) Series 3: V.1- 1918- Volume(issue)/page/year: 29,1363,1946 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 4730 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(7),46,1986

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2520 mg/kg

TOXIC EFFECTS :: Behavioral - muscle contraction or spasticity

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(3),79,1980

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 11 gm/kg

TOXIC EFFECTS :: Behavioral - muscle contraction or spasticity

REFERENCE :: GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 45(3),79,1980

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 10 mL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: UCDS** Union Carbide Data Sheet. (Union Carbide Corp., 39 Old Ridgebury Rd., Danbury, CT 06817) Volume(issue)/page/year: 4/21/1967

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 1580 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Gastrointestinal - other changes Kidney, Ureter, Bladder - other changes

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 23,259,1941

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: >1 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 30(7),46,1986 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 28 gm/kg/2W-C

TOXIC EFFECTS :: Behavioral - food intake (animal) Kidney, Ureter, Bladder - changes in bladder weight

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 6(1),53,1987 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M0259 No. of Facilities: 1842 (estimated) No. of Industries: 27 No. of Occupations: 44 No. of Employees: 23845 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - M0259 No. of Facilities: 2702 (estimated) No. of Industries: 51 No. of Occupations: 58 No. of Employees: 64304 (estimated) No. of Female Employees: 8631 (estimated)

三异丙醇胺安全信息

[ 符号 ]:

GHS07

[ 信号词 ]:
Warning

[ 危害声明 ]:
H319-H412

[ 警示性声明 ]:
P273-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant;

[ 风险声明 (欧洲) ]:
R36;R52/53

[ 安全声明 (欧洲) ]:
S26-S61

[ 危险品运输编码 ]:
UN 3259 8/PG 2

[ WGK德国 ]:
1

[ RTECS号 ]:
UB8750000

[ 包装等级 ]:
III

[ 危险类别 ]:
8.0

[ 海关编码 ]:
2922199090

三异丙醇胺合成路线

三异丙醇胺制备

由环氧丙烷与氨反应制得，是生产异丙醇胺的联产品。

三异丙醇胺海关

[ 海关编码 ]: 2922199090

[ 中文概述 ]:
2922199090. 其他氨基醇及其醚，酯和它们的盐（但含一种以上含氧基的除外）. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 乙醇胺及其盐应报明色度, 乙醇胺及其盐应报明包装

[ Summary ]:
2922199090. other amino-alcohols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

三异丙醇胺文献

Initiation activity of endogenously synthesized N-nitrosobis(2-hydroxypropyl)amine in the rat liver.

Cancer Lett. 45(3) , 221-5, (1989)

The initiation potential of N-nitrosobis(2-hydroxypropyl)amine (NDHPA) endogenously synthesized from bis(2-hydroxypropyl)amine (DHPA) or tris(2-hydroxypropyl)amine (THPA) in the presence of sodium nit...

Autoclavable highly cross-linked polyurethane networks in ophthalmology.

Biomaterials 14(14) , 1089-97, (1993)

Highly cross-linked aliphatic polyurethane networks have been prepared by the bulk step reaction of low molecular weight polyols and hexamethylenediisocyanate (HDI). These polyurethane networks are op...

Gas chromatographic determination of N-nitrosodialkanolamines in herbicide Di- or trialkanolamine formulations.

J. Assoc. Off. Anal. Chem. 71(2) , 328-33, (1988)

A modified method is presented to determine trace quantities of N-nitrosodiethanolamine (NDElA) and N-nitrosodiisopropanolamine (NDiPlA) in the triisopropanolamine (TiPlA) formulation of a mixture of ...

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