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4 -(马来酰亚胺基)苯基异氰酸酯

4 -(马来酰亚胺基)苯基异氰酸酯名称

[ CAS 号 ]:
123457-83-0

[ 中文名 ]:
N-(P-马来酰亚胺基苯基)异氰酸酯

[ 英文名 ]:
4-(MALEINIMIDO)PHENYL ISOCYANATE

[中文别名 ]:

N-(p-马来酰亚胺基苯基)异氰酸酯

[英文别名 ]:

4-(Maleinimido)phenyl isocyanate
1-(4-Isocyanatophenyl)-1H-pyrrole-2,5-dione
1-(4-isocyanatophenyl)pyrrole-2,5-dione
1H-Pyrrole-2,5-dione, 1-(4-isocyanatophenyl)-

4 -(马来酰亚胺基)苯基异氰酸酯物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
375.4±25.0 °C at 760 mmHg

[ 熔点 ]:
120-125ºC

[ 分子式 ]:
C₁₁H₆N₂O₃

[ 分子量 ]:
214.177

[ 闪点 ]:
180.8±23.2 °C

[ 精确质量 ]:
214.037842

[ PSA ]:
66.81000

[ LogP ]:
1.45

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.641

[ 储存条件 ]:
2-8°C

4 -(马来酰亚胺基)苯基异氰酸酯MSDS

4 -(马来酰亚胺基)苯基异氰酸酯安全信息

[ 符号 ]:

GHS07, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H312-H315-H317-H319-H332-H334-H335

[ 警示性声明 ]:
P261-P280-P305 + P351 + P338-P342 + P311

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
S22

[ 危险品运输编码 ]:
NONH for all modes of transport

4 -(马来酰亚胺基)苯基异氰酸酯合成路线

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4 -(马来酰亚胺基)苯基异氰酸酯文献

p-maleimidophenyl isocyanate: a novel heterobifunctional linker for hydroxyl to thiol coupling.

Bioconjug. Chem. 4 , 212, (1993)

p-Maleimidophenyl isocyanate (PMPI, 1) is a heterobifunctional cross-linking agent useful for thiol to hydroxyl coupling. Several maleimide-activated compounds were prepared and characterized and then...

Cys-93-betabeta-succinimidophenyl polyethylene glycol 2000 hemoglobin A. Intramolecular cross-bridging of hemoglobin outside the central cavity.

J. Biol. Chem. 275 , 5527, (2000)

Bis(maleidophenyl)-PEG2000 (Bis-Mal-PEG2000), a new bifunctional protein cross-linker targeted to sulfhydryl groups, introduces intra-tetrameric cross-links into oxy-HbA in nearly quantitative yields....

Synthesis of enzyme-degradable, peptide-cross-linked dextran hydrogels.

Bioconjug. Chem. 18(3) , 874-85, (2007)

Hydrogels derived from synthetic polymers have been previously engineered to degrade under the activity of matrix metalloproteinases (MMPs). It is believed that these systems can act as extracellular-...

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