新戊二醇(NPG)

新戊二醇(NPG)用途

【用途一】
主要用于制造树脂、增塑剂和表面活性剂
【用途二】
新戊二醇的用途很广，主要作为生产不饱和聚酯树脂、无油醇酸树脂、聚氨酯泡沫塑料和弹性体的增塑剂，高级润滑油的添加剂及其他精细化学品。新戊二醇是优良的溶剂，可用于芳烃和环烷基碳氢化合物的选择分离。新戊二醇具有耐水、耐化学药品、耐候性。其氨基烘漆具有良好的保光性并且不泛黄。还可用作生产阻聚剂、稳定剂、杀虫剂的原料。
【用途三】
增塑剂。有机合成。聚酯合成原料。

新戊二醇(NPG)名称

[ CAS 号 ]:
126-30-7

[ 中文名 ]:
2,2-二甲基-1,3-丙二醇

[ 英文名 ]:
Neopentyl glycol

[中文别名 ]:

[英文别名 ]:

Neopentyl glycol (NPG)
2,2-Bis(hydroxymethyl)propane
1,3-Propanediol, 2,2-dimethyl-
NPG Glycol,Neopentylglycol
2,2-Dihydroxy-2,2-dimethylpropane
2,2-dimethylpropane-1,3-diol
Neopentyl glycol
EINECS 204-781-0
2,2-Dimethyl-1,3-propanediol
MFCD00004685

新戊二醇(NPG)物理化学性质

[ 密度 ]:
1.06

[ 沸点 ]:
208 ºC

[ 熔点 ]:
122-128 ºC

[ 分子式 ]:
C₅H₁₂O₂

[ 分子量 ]:
104.148

[ 闪点 ]:
107.2±0.0 °C

[ 精确质量 ]:
104.083733

[ PSA ]:
40.46000

[ LogP ]:
-0.34

[ 外观性状 ]:
白色结晶固体

[ 蒸汽密度 ]:
3.6 (vs air)

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.445

[ 储存条件 ]:
存放于惰性气体之中;避免湿气 (吸湿)

[ 稳定性 ]:
Stable. Incompatible with strong oxidizing agents, acetic anhydride, acid chlorides, moisture. Combustible.

[ 水溶解性 ]:
830 g/L (20 ºC)

新戊二醇(NPG)MSDS

详细MSDS(安全技术说明书)

新戊二醇(NPG)毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TY5775000

CHEMICAL NAME :: 1,3-Propanediol, 2,2-dimethyl-

CAS REGISTRY NUMBER :: 126-30-7

BEILSTEIN REFERENCE NO. :: 0605291

LAST UPDATED :: 199706

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C5-H12-O2

MOLECULAR WEIGHT :: 104.17

WISWESSER LINE NOTATION :: Q1X1&1&1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 39000 ppm/6H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: KODAK* Kodak Company Reports. (343 State St., Rochester, NY 14650) Volume(issue)/page/year: 21MAY1971 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83578 No. of Facilities: 497 (estimated) No. of Industries: 11 No. of Occupations: 37 No. of Employees: 15135 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83578 No. of Facilities: 367 (estimated) No. of Industries: 11 No. of Occupations: 14 No. of Employees: 6957 (estimated) No. of Female Employees: 1200 (estimated)

新戊二醇(NPG)安全信息

[ 符号 ]:

GHS05

[ 信号词 ]:
Danger

[ 危害声明 ]:
H318

[ 警示性声明 ]:
P280-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Gloves

[ 危害码 (欧洲) ]:
Xi:Irritant

[ 风险声明 (欧洲) ]:
R36

[ 安全声明 (欧洲) ]:
S26-S36-S39

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ RTECS号 ]:
TY5775000

[ 海关编码 ]:
2905399090

新戊二醇(NPG)合成路线

详细合成路线

新戊二醇(NPG)上下游产品

新戊二醇(NPG)上游产品

新戊二醇(NPG)下游产品

新戊二醇(NPG)制备

1.甲酸钠法　异丁醛与甲醛在30-35℃、pH值9-11、碱催化剂存在下缩合生成羟基叔丁醛，与过量甲醛在强碱条件下还原成新戊二醇，甲醛则被氧化，并与碱作用生成甲酸钠。反应液用甲酸中和，减压蒸馏脱水，浓缩液经分层萃取，除去甲酸钠后，冷却、结晶、分离，得成品。

2.加氢法　由异丁醛和甲醛经缩合，得羟基新戊醛，再经加氢还原而得。

3.制法：

于装有搅拌器、温度计、滴液漏斗、回流冷凝器的反应瓶中，加入乙醇^①800mL，氢氧化钾175g(3mol),冰水浴冷却，滴加由甲醛(40%,500mL,6.4mol)、异丁醛(2)180g（2.5mol）和适量乙醇配成的溶液，控制反应液温度在30℃左右，加完后继续搅拌反应2h。而后回流反应5h。减压回收乙醇和水。冷却，用乙醚提取四次。蒸馏回收乙醚。剩余物用苯重结晶，得新戊二醇(1)。收率50%。注：①也可用甲醇代替乙醇。该反应为放热反应。反应中生成甲酸钾，可回收。

新戊二醇(NPG)海关

[ 海关编码 ]: 2905399090

[ 中文概述 ]:
2905399090 其他二元醇。监管条件:AB(入境货物通关单,出境货物通关单)。增值税率:17.0%。退税率:9.0%。最惠国关税:5.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ 监管条件 ]: A.入境货物通关单 B.出境货物通关单

[ 检验检疫 ]: R.进口食品卫生监督检验 S.出口食品卫生监督检验 M.进口商品检验 N.出口商品检验

[ Summary ]:
2905399090 other diols。supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward)。VAT:17.0%。tax rebate rate:9.0%。MFN tariff:5.5%。general tariff:30.0%

新戊二醇(NPG)文献

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Occurrence of short chain aliphatic diols in human blood: identification by gas chromatography-mass spectrometry.

Clin. Chim. Acta 155(2) , 117-22, (1986)

Patients attending a general hospital for various reasons were screened for raised serum gamma glutamyltransferase (gamma-GT) and positive blood alcohol concentration (BAC). The results served as obje...

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