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N-Fmoc-D-1,2,3,4-四氢异喹啉-3-羧酸

N-Fmoc-D-1,2,3,4-四氢异喹啉-3-羧酸名称

[ CAS 号 ]:
130309-33-0

[ 中文名 ]:
N-Fmoc-D-1,2,3,4-四氢异喹啉-3-羧酸

[ 英文名 ]:
Fmoc-D-Tic-OH

[中文别名 ]:

FMOC-D-四氢异喹啉-3-羧酸

[英文别名 ]:

Fmoc-D-Tic-OH
MFCD00144345

N-Fmoc-D-1,2,3,4-四氢异喹啉-3-羧酸物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
629.9±55.0 °C at 760 mmHg

[ 熔点 ]:
160-164 °C

[ 分子式 ]:
C₂₅H₂₁NO₄

[ 分子量 ]:
399.439

[ 闪点 ]:
334.7±31.5 °C

[ 精确质量 ]:
399.147064

[ PSA ]:
66.84000

[ LogP ]:
4.84

[ 外观性状 ]:
白色结晶粉末

[ 蒸汽压 ]:
0.0±1.9 mmHg at 25°C

[ 折射率 ]:
1.657

[ 储存条件 ]:
2-8°C

N-Fmoc-D-1,2,3,4-四氢异喹啉-3-羧酸MSDS

详细MSDS(安全技术说明书)

N-Fmoc-D-1,2,3,4-四氢异喹啉-3-羧酸安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

N-Fmoc-D-1,2,3,4-四氢异喹啉-3-羧酸文献

Bradykinin receptor antagonists containing N-substituted amino acids: in vitro and in vivo B(2) and B(1) receptor antagonist activity.

J. Med. Chem. 39 , 1472, (1996)

We report a systematic probing of the structural requirements of the bradykinin (BK) type 2 (B(2)) receptor for antagonist activity by incorporating N-alkyl-amino acid residues at positions 7 and 8 of...

Design and synthesis of new linear and cyclic bradykinin antagonists.

J. Med. Chem. 39 , 2095, (1996)

We report here on the synthesis and pharmacological properties of a new series of small linear and cyclic peptides derived from the five C-terminal amino acid residues of second-generation bradykinin ...

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