4,6-bis(aziridin-1-yl)-2,5-dichloropyrimidine

名称

[ CAS 号 ]:
13150-18-0

[ 英文名 ]:
4,6-bis(aziridin-1-yl)-2,5-dichloropyrimidine

[英文别名 ]:

4,6-bis-aziridin-1-yl-2,5-dichloro-pyrimidine

物理化学性质

[ 密度 ]:
1.675g/cm3

[ 沸点 ]:
472.9ºC at 760mmHg

[ 分子式 ]:
C₈H₈Cl₂N₄

[ 分子量 ]:
231.08200

[ 闪点 ]:
239.8ºC

[ 精确质量 ]:
230.01300

[ PSA ]:
31.80000

[ LogP ]:
1.55340

[ 蒸汽压 ]:
4.12E-09mmHg at 25°C

[ 折射率 ]:
1.715

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV7072100

CHEMICAL NAME :: Pyrimidine, 4,6-bis(1-aziridinyl)-2,5-dichloro-

CAS REGISTRY NUMBER :: 13150-18-0

BEILSTEIN REFERENCE NO. :: 0656736

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C8-H8-Cl2-N4

MOLECULAR WEIGHT :: 231.10

WISWESSER LINE NOTATION :: T6N CNJ BG D- AT3NTJ& EG F- AT3NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10700 ug/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 5,101,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 20 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 5,101,1970