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α2β1 Integrin Ligand Peptide

α2β1 Integrin Ligand Peptide用途

α2β1 Integrin Ligand Peptide在细胞膜表面与 α2β1 整合素受体相互作用,进入细胞介导细胞外信号。α2β1 Integrin Ligand Peptide是一种潜在的胶原受体拮抗剂。

α2β1 Integrin Ligand Peptide名称

[ CAS 号 ]:
134580-64-6

[ 英文名 ]:
α2β1 Integrin Recognition Sequence

[英文别名 ]:

L-|A-Aspartylglycyl-L-|A-glutamyl-L-alanine
|A2|A1 Integrin Recognition Sequence
H-Asp-Gly-Glu-Ala-OH
DGEA

α2β1 Integrin Ligand Peptide生物活性

[ 描述 ]:

α2β1 Integrin Ligand Peptide在细胞膜表面与 α2β1 整合素受体相互作用,进入细胞介导细胞外信号。α2β1 Integrin Ligand Peptide是一种潜在的胶原受体拮抗剂。

[ 相关类别 ]:

研究领域 >> 其他

信号通路 >> 细胞骨架 >> Integrin

[参考文献]

[1]. Graham KL, et al. Effects on rotavirus cell binding and infection of monomeric and polymeric peptides containing alpha2beta1 and alphaxbeta2 integrin ligand sequences. J Virol. 2004 Nov;78(21):11786-97.

α2β1 Integrin Ligand Peptide物理化学性质

[ 分子式 ]:
C₁₄H₂₂N₄O₉

[ 分子量 ]:
390.34600

[ 精确质量 ]:
390.13900

[ PSA ]:
235.69000

[ LogP ]:
0.06470

α2β1 Integrin Ligand PeptideMSDS

详细MSDS(安全技术说明书)

α2β1 Integrin Ligand Peptide安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

α2β1 Integrin Ligand Peptide文献

Identification of a tetrapeptide recognition sequence for the alpha 2 beta 1 integrin in collagen.

J. Biol. Chem. 266 , 7363-7367, (1991)

The alpha 2 beta 1 integrin serves as either a specific cell surface receptor for collagen or as both a collagen and laminin receptor depending upon the cell type. Recently we established that the alp...

RGDS and DGEA-induced [Ca2+]i signalling in human dermal fibroblasts.

Biochim. Biophys. Acta Mol. Cell Res. 1746(1) , 28-37, (2005)

A pulse of short peptides, RGDS and DGEA in the millimolar range, immediately elicits in normal human fibroblasts a transient increase of intracellular Ca2+ ([Ca2+]i). In the present study, we show th...

Glioma initiating cells form a differentiation niche via the induction of extracellular matrices and integrin αV.

PLoS ONE 8 , e59558, (2013)

Glioma initiating cells (GICs) are considered responsible for the therapeutic resistance and recurrence of malignant glioma. To clarify the molecular mechanism of GIC maintenance/differentiation, we e...

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