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(D-ARG0,HYP3,D-PHE7,LEU8)-BRADYKININ

(D-ARG0,HYP3,D-PHE7,LEU8)-BRADYKININ名称

[ CAS 号 ]:
135701-67-6

[ 中文名 ]:
(D-ARG0,HYP3,D-PHE7,LEU8)-BRADYKININ

[ 英文名 ]:
(D-Arg0,Hyp3,D-Phe7,Leu8)-Bradykinin

[英文别名 ]:

D-ARG-ARG-PRO-HYP-GLY-PHE-SER-D-PHE-LEU-ARG
Leu(8)]-bradykinin B2
D-ARG-[HYP3,D-PHE7,LEU8]-BRADYKININ
H-D-ARG-ARG-PRO-HYP-GLY-PHE-SER-D-PHE-LEU-ARG-OH
D-Arg(0)[Hyp(3),D-Phe(7),Leu(8)]-BK
Aaphgpspla
(D-ARG0,HYP3,D-PHE7,LEU8)-BRADYKININ
bradykinin,Arg-Hyp(3)-Phe(7)-Leu(8)
D-Arg(0)[Hyp(3)

(D-ARG0,HYP3,D-PHE7,LEU8)-BRADYKININ物理化学性质

[ 密度 ]:
1.5±0.1 g/cm3

[ 分子式 ]:
C₅₇H₈₉N₁₉O₁₃

[ 分子量 ]:
1248.436

[ 精确质量 ]:
1247.688721

[ PSA ]:
533.80000

[ LogP ]:
-1.49

[ 折射率 ]:
1.681

(D-ARG0,HYP3,D-PHE7,LEU8)-BRADYKININ安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

(D-ARG0,HYP3,D-PHE7,LEU8)-BRADYKININ合成路线

详细合成路线

(D-ARG0,HYP3,D-PHE7,LEU8)-BRADYKININ文献

New highly potent bradykinin B2 receptor antagonists.

Agents Actions 34 , 138-141, (1991)

pA2 values of new B2 receptor antagonists ranging from 7.51 to 8.86 were measured on the rabbit jugular vein, while lower values were observed in the other preparations (for instance, the hamster urin...

Non-selectivity of new bradykinin antagonists for B1 receptors.

Life Sci. 51 , PL 125, (1992)

Two new B1 receptor antagonists, [Hyp3,Thi5,DTic7,Oic8]desArg9-BK and DArg[Hyp3,Thi5,DTic7,Oic8]desArg9-BK were tested in vitro on the rabbit jugular vein and the guinea pig ileum (preparations contai...

A new class of bradykinin antagonists: synthesis and in vitro activity of bissuccinimidoalkane peptide dimers.

J. Med. Chem. 35 , 1563, (1992)

A systematic study on the dimerization of the bradykinin (BK) antagonist D-Arg0-Arg1-Pro2-Hyp3-Gly4-Phe5-Ser6-D-Phe 7-Leu8-Arg9 has been performed. The first part of this study involved compounds wher...

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