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佐米曲普坦

佐米曲普坦用途

【用途一】
治疗偏头痛药物

佐米曲普坦名称

[ CAS 号 ]:
139264-17-8

[ 中文名 ]:
佐米曲普坦

[ 英文名 ]:
Zolmitriptan

[中文别名 ]:

[英文别名 ]:

BW 311C90
Zomigoro
Zolmitriptan
Zomigon
AscoTop
Zomig
MFCD00871503

佐米曲普坦物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
563.3±38.0 °C at 760 mmHg

[ 熔点 ]:
136-141ºC

[ 分子式 ]:
C₁₆H₂₁N₃O₂

[ 分子量 ]:
287.357

[ 闪点 ]:
294.5±26.8 °C

[ 精确质量 ]:
287.163391

[ PSA ]:
57.36000

[ LogP ]:
1.64

[ 外观性状 ]:
固体;White to Orange to Green powder to crystal

[ 蒸汽压 ]:
0.0±1.5 mmHg at 25°C

[ 折射率 ]:
1.620

[ 储存条件 ]:
Refrigerator

佐米曲普坦MSDS

佐米曲普坦安全信息

[ 危害码 (欧洲) ]:
Xi: Irritant;

[ 风险声明 (欧洲) ]:
R36/37/38

[ 安全声明 (欧洲) ]:
S26-S36

[ 危险品运输编码 ]:
NONH for all modes of transport

[ RTECS号 ]:
RQ2707000

[ 海关编码 ]:
2934999090

佐米曲普坦合成路线

佐米曲普坦上下游产品

佐米曲普坦上游产品

佐米曲普坦下游产品

佐米曲普坦海关

[ 海关编码 ]: 2934999090

[ 中文概述 ]:
2934999090. 其他杂环化合物. 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

佐米曲普坦文献

Bioenhanced sublingual tablet of drug with limited permeability using novel surfactant binder and microencapsulated polysorbate: In vitro/in vivo evaluation.

Eur. J. Pharm. Biopharm. 94 , 386-92, (2015)

Formulation of sublingual tablets of drugs with limited permeability poses a great challenge due to their poor absorption. In this study, bioenhanced sublingual tablets (BESTs) of zolmitriptan were pr...

Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure.

PLoS ONE 8(1) , e52683, (2013)

Only a limited proportion of patients needing pharmacological control of portal hypertension are hemodynamic responders to propranolol. Here we analyzed the effects of zolmitriptan on portal pressure ...

Preparation and evaluation of zolmitriptan submicron emulsion for rapid and effective nasal absorption in beagle dogs.

Drug Dev. Ind. Pharm. 37(12) , 1509-16, (2011)

Submicron emulsion was prepared for rapid and effective nasal absorption of zolmitriptan (ZT). The different charge inducers and pH values of the formulations were evaluated to optimize the formulatio...

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