硫酸双氢链霉素
硫酸双氢链霉素名称
[ CAS 号 ]:
1425-61-2
[ 中文名 ]:
硫酸二氢链霉素
[ 英文名 ]:
dihydrostreptomycin sesquisulfate salt
[中文别名 ]:
[英文别名 ]:
- didromycin
- dihydrostreptomycin3/2sulfate
- didromycine
- panstreptin
- dihydrostreptomycin sesquisulfate
- Sol-Mycin
- Prestwick_173
- dihydrostreptomycin,sulfate
- Double-Mycin
- dihydrostreptomycin solution
硫酸双氢链霉素物理化学性质
[ 沸点 ]:
954.5ºC at 760 mmHg
[ 分子式 ]:
C42H88N14O36S3
[ 分子量 ]:
1461.415
[ 闪点 ]:
531.1ºC
[ 精确质量 ]:
1460.464722
[ PSA ]:
918.12000
[ 外观性状 ]:
crystalline
[ 储存条件 ]:
2-8°C
[ 水溶解性 ]:
H2O: 50 mg/mL, clear, faintly yellow
硫酸双氢链霉素毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- WK4950000
- CHEMICAL NAME :
- Streptomycin, dihydro-, sulfate
- CAS REGISTRY NUMBER :
- 1425-61-2
- LAST UPDATED :
- 199112
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C21-H41-N7-O12.xH2-O4-S
- MOLECULAR WEIGHT :
- 1270.25
- WISWESSER LINE NOTATION :
- T6OTJ CM1 DQ EQ F1Q BO- CT5OTJ DQ D1Q E1 BO- AL6TJ BQ CQ DMYZUM EQ FMYZUM &WSQQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 12,597,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >600 mg/kg
- TOXIC EFFECTS :
- Behavioral - ataxia
- REFERENCE :
- ANTCAO Antibiotics and Chemotherapy (Washington, DC). (Washington, DC) V.1-12, 1951-62. For publisher information, see CLMEA3. Volume(issue)/page/year: 1,49,1951
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1380 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- RPOBAR Research Progress in Organic-Biological and Medicinal Chemistry. (New York, NY) V.1-3, 1964-72. Discontinued. Volume(issue)/page/year: 2,285,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 761 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 18,444,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 137 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ANTBAL Antibiotiki. (Moscow, USSR) V.1-29, 1956-84. For publisher information, see AMBIEH. Volume(issue)/page/year: 18,444,1973 *** REVIEWS *** TOXICOLOGY REVIEW PMMDAE Panminerva Medica. (Edizioni Minerva Medica, Casella Postale 491, Turin, Italy) V.1- 1959- Volume(issue)/page/year: 16,9,1974
硫酸双氢链霉素安全信息
[ WGK德国 ]:
3
[ RTECS号 ]:
WK2236000
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