SGK1 Inhibitor

SGK1 inhibitor is an inhibitor of serum- and glucocorticoid-regulated kinase 1 (SGK1) and SGK2. It is selective for SGK1 and SGK2 over SGK3 in the presence of a high concentration of ATP. SGK1 inhibitor prevents phosphorylation of GSK3β in U2OS cells and decreases cell viability in BYL719-insensitive HCC1954 cells when used in combination with the PI3Kα inhibitor BYL719. SGK1 inhibitor reduces tumor growth in an HCC1954 mouse xenograft model when administered in combination with BYL719.

[ 密度 ]:
1.7±0.1 g/cm3

[ 沸点 ]:
730.5±70.0 °C at 760 mmHg

[ 分子式 ]:
C₁₇H₁₂Cl₂N₆O₂S

[ 分子量 ]:
435.287

[ 闪点 ]:
395.6±35.7 °C

[ 精确质量 ]:
434.011963

[ LogP ]:
3.81

[ 蒸汽压 ]:
0.0±2.4 mmHg at 25°C

[ 折射率 ]:
1.750

公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：SGK1 Inhibitor

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公司名：上海脉铂医药科技有限公司

区域：上海市嘉定区

价格：
￥2255.0/5mg ￥3654.0/10mg ￥451.0/1mg ￥需询单/1mg

联系人：李先生

产品详情：SGK1 Inhibitor

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