<生产厂家价格>

G PROTEIN ANTAGONIST

G PROTEIN ANTAGONIST用途

G蛋白拮抗肽是一种P物质相关肽,它抑制G蛋白与受体的结合。G蛋白拮抗肽竞争性可逆地抑制Gi或Go的M2受体激活,并通过β肾上腺素受体抑制Gs的激活。

G PROTEIN ANTAGONIST名称

[ CAS 号 ]:
143675-79-0

[ 中文名 ]:
G PROTEIN ANTAGONIST

[ 英文名 ]:
G Protein Antagonist

[英文别名 ]:

PYR-GLN-D-TRP-PHE-D-TRP-D-TRP-MET-NH2
pglu-gln-d-trp-phe-d-trp-d-trp-met-nh2
G PROTEIN ANTAGONIST
PROTEIN G ANTAGONIST 2
GP ANTAGONIST-2
pGlu-Gln-D-Trp-Phe-D-Trp-D-Trp-Met-NH2
[pGlu5,D-Trp7,9,10]-Substance P Fragment 5-11
G-PROTEIN ANTAGONIST-2

G PROTEIN ANTAGONIST生物活性

[ 描述 ]:

G蛋白拮抗肽是一种P物质相关肽,它抑制G蛋白与受体的结合。G蛋白拮抗肽竞争性可逆地抑制Gi或Go的M2受体激活,并通过β肾上腺素受体抑制Gs的激活。

[ 相关类别 ]:

信号通路 >> 神经信号通路 >> mAChR

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 由mAChR

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 肾上腺素能受体

G PROTEIN ANTAGONIST物理化学性质

[ 分子式 ]:
C₅₇H₆₄N₁₂O₉S

[ 分子量 ]:
1093.26000

[ 精确质量 ]:
1092.46000

[ PSA ]:
362.55000

[ LogP ]:
6.16720

[ 外观性状 ]:
固体

[ 储存条件 ]:
2-8°C，密封，干燥

G PROTEIN ANTAGONIST安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 安全声明 (欧洲) ]:
22-24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

G PROTEIN ANTAGONIST文献

G protein antagonists. A novel hydrophobic peptide competes with receptor for G protein binding.

J. Biol. Chem. 267 , 16237, (1992)

A substance P (SP) analog, [D-Pro4,D-Trp7,9,10] SP4-11, is known to inhibit the actions of various structurally unrelated messenger molecules as well as SP. Our studies on the effects of this peptide ...

更多文献