4-(aziridin-1-yl)-6-chloropyrimidine

4-(aziridin-1-yl)-6-chloropyrimidine名称

[ CAS 号 ]:
14673-04-2

[ 英文名 ]:
4-(aziridin-1-yl)-6-chloropyrimidine

[英文别名 ]:

Pyrimidine,4-(1-aziridinyl)-6-chloro
4-Ethyleneimino-6-chloropyrimidine
4-(1-Aziridinyl)-6-chloropyrimidine
4-aziridin-1-yl-6-chloro-pyrimidine

4-(aziridin-1-yl)-6-chloropyrimidine物理化学性质

[ 密度 ]:
1.455g/cm3

[ 沸点 ]:
303.4ºC at 760mmHg

[ 分子式 ]:
C₆H₆ClN₃

[ 分子量 ]:
155.58500

[ 闪点 ]:
137.3ºC

[ 精确质量 ]:
155.02500

[ PSA ]:
28.79000

[ LogP ]:
1.01500

[ 蒸汽压 ]:
0.000933mmHg at 25°C

[ 折射率 ]:
1.635

4-(aziridin-1-yl)-6-chloropyrimidine毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: UV6803000

CHEMICAL NAME :: Pyrimidine, 4-(1-aziridinyl)-6-chloro-

CAS REGISTRY NUMBER :: 14673-04-2

BEILSTEIN REFERENCE NO. :: 0908490

LAST UPDATED :: 199612

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C6-H6-Cl-N3

MOLECULAR WEIGHT :: 155.60

WISWESSER LINE NOTATION :: T6N CNJ DG F- AT3NTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 96 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 5,101,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 245 mg/kg

TOXIC EFFECTS :: Behavioral - changes in motor activity (specific assay) Behavioral - muscle contraction or spasticity Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 5,101,1970