10H-Phenothiazine,2-methoxy-10-[2-(1-methyl-2-piperidinyl)ethyl]-

名称

[ CAS 号 ]:
14759-04-7

[ 英文名 ]:
10H-Phenothiazine,2-methoxy-10-[2-(1-methyl-2-piperidinyl)ethyl]-

[英文别名 ]:

KS 33
Oxyridazine
Oxiridazinum

物理化学性质

[ 密度 ]:
1.137g/cm3

[ 沸点 ]:
503.5ºC at 760mmHg

[ 分子式 ]:
C₂₁H₂₆N₂OS

[ 分子量 ]:
354.50900

[ 闪点 ]:
258.3ºC

[ 精确质量 ]:
354.17700

[ PSA ]:
41.01000

[ LogP ]:
5.17520

[ 蒸汽压 ]:
2.89E-10mmHg at 25°C

[ 折射率 ]:
1.597

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: SP0875000

CHEMICAL NAME :: Phenothiazine, 2-methoxy-10-(2-(1-methyl-2-piperidyl)ethyl)-

CAS REGISTRY NUMBER :: 14759-04-7

BEILSTEIN REFERENCE NO. :: 6118065

LAST UPDATED :: 199612

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C21-H26-N2-O-S

MOLECULAR WEIGHT :: 354.55

WISWESSER LINE NOTATION :: T C666 BN ISJ EO1 B2- BT6NTJ A1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1130 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 27ZQAG "Psychotropic Drugs and Related Compounds," 2nd ed., Usdin, E., and D.H. Efron, Washington, DC, 1972 Volume(issue)/page/year: -,27,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 760 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: NIGZAY Niigata Igakkai Zasshi. Niigata Medical Journal. (Niigata Igakkai, 1, Asahi-machi, Niigata 951, Japan) V.60- 1946- Volume(issue)/page/year: 82,607,1968

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 516 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 65(2),104S,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 42 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - tremor Behavioral - convulsions or effect on seizure threshold

REFERENCE :: NYKZAU Nippon Yakurigaku Zasshi. Japanese Journal of Pharmacology. (Nippon Yakuri Gakkai, c/o Kyoto Daigaku Igakubu Yakurigaku Kyoshitsu, Konoe-cho, Yoshida, Sakyo-ku, Kyoto 606, Japan) V.40- 1944- Volume(issue)/page/year: 65(2),104S,1969

安全信息

[ 海关编码 ]:
2934300000

海关

[ 海关编码 ]: 2934300000

[ 中文概述 ]:
2934300000. 含一个吩噻嗪环系的化合物(吩噻嗪环系不论是否氢化,化合物未经进一步稠合的 ). 增值税率:17.0%. 退税率:13.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934300000. other compounds containing in the structure a phenothiazine ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%