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2-甲基-2-苯基琥珀酰亚胺

2-甲基-2-苯基琥珀酰亚胺名称

[ CAS 号 ]:
1497-17-2

[ 中文名 ]:
Alpha-甲基-Alpha-苯基丁二酰亚胺

[ 英文名 ]:
2-methyl-2-phenylsuccinimide

[中文别名 ]:

[英文别名 ]:

3-Phenyl-3-methylpyrrolidine-2,5-dione
3-Methyl-3-phenyl-pyrrolidin-2,5-dion
n-desmethylmethsuximide
A-METHYL-A-PHENYLSUCCINIMIDE
Mesuximide,M(nor-)
EINECS 216-091-7
3-Methyl-3-phenyl-2,5-pyrrolidinedione
MFCD00005496
3-methyl-3-phenylpyrrolidine-2,5-dione
Normesuximide

2-甲基-2-苯基琥珀酰亚胺物理化学性质

[ 密度 ]:
1.179g/cm3

[ 沸点 ]:
371.1ºC at 760mmHg

[ 熔点 ]:
83-85ºC(lit.)

[ 分子式 ]:
C₁₁H₁₁NO₂

[ 分子量 ]:
189.21100

[ 闪点 ]:
165.3ºC

[ 精确质量 ]:
189.07900

[ PSA ]:
46.17000

[ LogP ]:
1.31960

[ 蒸汽压 ]:
1.06E-05mmHg at 25°C

[ 折射率 ]:
1.55

[ 储存条件 ]:
室温，干燥

2-甲基-2-苯基琥珀酰亚胺MSDS

详细MSDS(安全技术说明书)

2-甲基-2-苯基琥珀酰亚胺安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

[ 海关编码 ]:
2925190090

2-甲基-2-苯基琥珀酰亚胺上下游产品

2-甲基-2-苯基琥珀酰亚胺上游产品

2-甲基-2-苯基琥珀酰亚胺下游产品

2-甲基-2-苯基琥珀酰亚胺海关

[ 海关编码 ]: 2925190090

[ 中文概述 ]:
2925190090 其他酰亚胺及其衍生物盐. 增值税率:17.0% 退税率:9.0% 监管条件:无最惠国关税:6.5% 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

2-甲基-2-苯基琥珀酰亚胺文献

Anticonvulsants Based on the α-Substituted Amide Group Pharmacophore Bind to and Inhibit Function of Neuronal Nicotinic Acetylcholine Receptors.

ACS Chem. Neurosci. 7 , 316-26, (2016)

Although the antiepileptic properties of α-substituted lactams, acetamides, and cyclic imides have been known for over 60 years, the mechanism by which they act remains unclear. I report here that the...

Differential effects of petit mal anticonvulsants and convulsants on thalamic neurones: calcium current reduction.

Br. J. Pharmacol. 100(4) , 800-6, (1990)

1. Succinimide derivatives can be either convulsant (tetramethylsuccinimide (TMS)), or anticonvulsant (ethosuximide (ES); alpha-methyl-alpha-phenylsuccinimide (MPS)). ES, an anticonvulsant succinimide...

Block of cloned human T-type calcium channels by succinimide antiepileptic drugs.

Mol. Pharmacol. 60(5) , 1121-32, (2001)

Inhibition of T-type Ca(2+) channels has been proposed to play a role in the therapeutic action of succinimide antiepileptic drugs. Despite the widespread acceptance of this hypothesis, recent studies...

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