左洛啡烷

左洛啡烷名称

[ CAS 号 ]:
152-02-3

[ 中文名 ]:
左洛啡烷

[ 英文名 ]:
levallorphan

[英文别名 ]:

左洛啡烷物理化学性质

[ 密度 ]:
1.14g/cm3

[ 沸点 ]:
433.5ºC at 760mmHg

[ 分子式 ]:
C19H25NO

[ 分子量 ]:
283.40800

[ 闪点 ]:
214.2ºC

[ 精确质量 ]:
283.19400

[ PSA ]:
23.47000

[ LogP ]:
3.57450

[ 蒸汽压 ]:
4.02E-08mmHg at 25°C

[ 折射率 ]:
1.614

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开存放

左洛啡烷毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QD0350000
CHEMICAL NAME :
Morphinan-3-ol, 17-allyl-, (-)-
CAS REGISTRY NUMBER :
152-02-3
LAST UPDATED :
199512
DATA ITEMS CITED :
5
MOLECULAR FORMULA :
C19-H25-N-O
MOLECULAR WEIGHT :
283.45
WISWESSER LINE NOTATION :
T6 G666/FQ 2AF Q FX ONT&TTJ IQ O2U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
949 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,-,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
185 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,140,1973
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
184 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
27ZIAQ "Drug Dosages in Laboratory Animals - A Handbook," Rev. ed., Barnes, C.D., and L.G. Eltherington, Berkeley, Univ. of California Press, 1973 Volume(issue)/page/year: -,-,1965
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
200 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
ANYAA9 Annals of the New York Academy of Sciences. (New York Academy of Sciences, 2 E. 63rd St., New York, NY 10021) V.1- 1877- Volume(issue)/page/year: 281,321,1976 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X4763 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 103 (estimated) No. of Female Employees: 52 (estimated)

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