甲草胺

甲草胺用途

【用途一】
用作芽前和芽后早期除草剂，可防除棉花、玉米、油菜、花生、大豆和甘蔗中一年生禾本科杂草和许多阔叶杂草
【用途二】
选择性旱地芽前除草剂。植物幼芽吸收药剂后，抑制蛋白酶的活力，阻碍蛋白质合成，致使杂草死亡。主要用于在出苗前土壤中萌发的杂草，对已出土杂草基本无效。防除大豆、棉花、甜菜、玉米、花生、油菜等旱地作物田间的一年出禾本科杂草，如稗草、牛筋草、秋稷、马唐、狗尾草、蟋蟀草、臂形草等，用量一般为20～30g有效成分/100m² 。如在大豆播种后至出苗前使用，用48%乳油30～45mL/100m² ，对水均匀喷雾土表。如玉米、蔬菜、花生播种出苗前或移栽前使用，用48%乳油30～38mL/100m² ，对水喷雾土表。
【用途三】
甲草胺被杂草的幼苗根部吸收，干扰核酸和蛋白质合成，阻止细胞增大，从而抑制根的伸长，然后影响全株生长，使杂草死亡。是一种选择性芽前除草剂，主要用于玉米、大豆、花生、甘蔗，也可用于非砂性土壤的棉花、油菜、马铃薯和洋葱、辣椒、甘蓝等作物，防治一年生杂草和某些阔叶杂草。在出芽前作土面处理。根据土壤类型用量为2.5～4kg（有效成分）/hm2，有效期为4-8星期。

甲草胺名称

[ CAS 号 ]:
15972-60-8

[ 中文名 ]:
甲草胺

[ 英文名 ]:
alachlor

[中文别名 ]:

[英文别名 ]:

Alanex
Satochlor
Methachlor
Chimiclor
G1VN1O1&R B2 F2
Lasso
Alachlore
alachlor
Lasagrin
Nitala

甲草胺物理化学性质

[ 密度 ]:
1.1±0.1 g/cm3

[ 沸点 ]:
404.0±45.0 °C at 760 mmHg

[ 熔点 ]:
39-42°C

[ 分子式 ]:
C₁₄H₂₀ClNO₂

[ 分子量 ]:
269.767

[ 闪点 ]:
198.1±28.7 °C

[ 精确质量 ]:
269.118256

[ PSA ]:
29.54000

[ LogP ]:
2.92

[ 外观性状 ]:
淡黄色晶体

[ 蒸汽压 ]:
0.0±0.9 mmHg at 25°C

[ 折射率 ]:
1.540

[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运

[ 水溶解性 ]:
0.024 g/100 mL

甲草胺MSDS

详细MSDS(安全技术说明书)

甲草胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AE1225000

CHEMICAL NAME :: Acetanilide, 2-chloro-2',6'-diethyl-N-(methoxymethyl)-

CAS REGISTRY NUMBER :: 15972-60-8

LAST UPDATED :: 199706

DATA ITEMS CITED :: 24

MOLECULAR FORMULA :: C14-H20-Cl-N-O2

MOLECULAR WEIGHT :: 269.80

WISWESSER LINE NOTATION :: G1VN1O1&R B2 F2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 930 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >23400 mg/m3/6H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 462 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5100 mg/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: 1200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 15120 mg/kg/17W-C

TOXIC EFFECTS :: Liver - changes in liver weight Endocrine - changes in thyroid weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2100 mg/kg/21D-I

TOXIC EFFECTS :: Liver - liver function tests impaired Liver - changes in liver weight

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 142 gm/kg/78W-C

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Mutation test systems - not otherwise specified

TYPE OF TEST :: Cytogenetic analysis

MUTATION DATA

TYPE OF TEST :: Cytogenetic analysis

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 10 mg/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 188,241,1987 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

甲草胺安全信息

[ 符号 ]:

GHS06, GHS08

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301 + H311 + H331-H370-H412

[ 警示性声明 ]:
P260-P280-P301 + P310 + P330-P302 + P352 + P312-P304 + P340 + P312-P308 + P311

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R22;R40;R43;R50/53

[ 安全声明 (欧洲) ]:
S36/37-S46-S60-S61-S62-S45

[ 危险品运输编码 ]:
UN 3077

[ RTECS号 ]:
AE1225000

[ 包装等级 ]:
I; II; III

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2924299034

甲草胺合成路线

详细合成路线

甲草胺上下游产品

甲草胺上游产品

甲草胺下游产品

甲草胺制备

1.苯胺与乙烯在高温、加压和催化剂存在下，制得2,6-二乙基苯胺；2,6-二乙基苯胺与氯乙酸、三氯化磷作用制得2，6-二乙基-N-氯代乙酰苯胺；甲醇与甲醛、氯化氢反应制得氯甲基甲醚；最后由氯甲基甲醚与2,6-二乙基-N-氯代乙酰苯胺合成甲草胺。

2.由2,6-二乙基胺与甲醛反应，制得2,6-二乙基-N-亚甲基苯胺。

将298g ( 1.82mo1 )2,6-二乙基一V一业甲基苯胺缓慢加入到20 6g(1.82mo1) 和210 g苯的混合液中，发热并反应，使温度约升至90 C;。然后冷却至35 C;，加250m工_干燥甲醉。加热回流，滴入190g(3.2mo1)二甲胺，同时反应液升温至70 ('，保温l Omin，冷却至约30 ('。将冷却后的反应混合物用1000mL水分2次洗涤。囚生成物为重油层，故采用减压脱洛，最终液温上升至9} <'。将蒸馏渣洛解在二甲基戊烷中，用干冰冷却，析出结晶，得甲草胺，熔点38 . 5-39 .5 ('，收率约85 %}

甲草胺海关

[ 海关编码 ]: 2924299034

[ 中文概述 ]:
2924299034 甲氯酰草胺、甲霜灵、环草隆等〔包括环莠隆、甲草胺、甲氧隆、克草胺、枯草隆〕。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量, 用途, 包装

[ 监管条件 ]: S.进出口农药登记证明

[ Summary ]:
2924299034 n-(3-chloro-4-methylphenyl)-2-methylpentanamide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0%

甲草胺文献

Environmental friendly method for urban wastewater monitoring of micropollutants defined in the Directive 2013/39/EU and Decision 2015/495/EU.

J. Chromatogr. A. 1418 , 140-9, (2015)

The fate and removal of organic micropollutants in the environment is a demanding issue evidenced by the recent European policy. This work presents an analytical method for the trace quantification of...

Influence of pesticide use in fruit orchards during blooming on honeybee mortality in 4 experimental apiaries.

Sci. Total Environ. 541 , 33-41, (2015)

Samples of dead honey bees (Apis mellifera L.) were collected periodically from 4 different locations during citrus and stone fruit trees blooming season to evaluate the potential impact of agrochemic...

Biodegradation of the acetanilide herbicides alachlor, metolachlor, and propachlor.

Crit. Rev. Microbiol 24(1) , 1-22, (1998)

Alachlor, metolachlor, and propachlor are detoxified in biological systems by the formation of glutathione-acetanilide conjugates. This conjugation is mediated by glutathione-S-transferase, which is p...

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甲草胺