Benzenemethanamine,N,N-bis(2-chloroethyl)-4-fluoro-, hydrochloride (1:1)
名称
[ CAS 号 ]:
1645-07-4
[ 英文名 ]:
Benzenemethanamine,N,N-bis(2-chloroethyl)-4-fluoro-, hydrochloride (1:1)
物理化学性质
[ 分子式 ]:
C11H15Cl3FN
[ 分子量 ]:
286.60100
[ 精确质量 ]:
285.02500
[ PSA ]:
3.24000
[ LogP ]:
3.90730
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DP1584000
- CHEMICAL NAME :
- Benzylamine, N,N-bis(2-chloroethyl)-p-fluoro-, hydrochloride
- CAS REGISTRY NUMBER :
- 1645-07-4
- LAST UPDATED :
- 199603
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C11-H14-Cl2-F-N.Cl-H
- MOLECULAR WEIGHT :
- 286.62
- WISWESSER LINE NOTATION :
- G2N2G1R DF &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 35 mg/kg/5W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 10500 ug/kg/5W-I
- TOXIC EFFECTS :
- Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis)
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Mold - Aspergillus nidulans
- DOSE/DURATION :
- 2500 umol/L
- REFERENCE :
- SOGEBZ Soviet Genetics. English translation of GNKAA5. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) V.2- 1966- Volume(issue)/page/year: 6,220,1970
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