5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮
5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮用途
用作钻井泥浆添加剂
5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮名称
[ CAS 号 ]:
1698-60-8
[ 中文名 ]:
氯草敏
[ 英文名 ]:
Chloridazon
[中文别名 ]:
[英文别名 ]:
- 5-Amino-4-chlor-2-phenylpyridazin-3(2H)-on
- Chloridazon
- pyrazon
- 3(2H)-Pyridazinone, 5-amino-4-chloro-2-phenyl-
- MFCD00055402
- PYRAMIN
- 5-amino-4-chloro-2-phenylpyridazin-3(2H)-one
- 5-Amino-4-chloro-2-phenyl-2H-pyridazin-3-one
- PAC
- EINECS 216-920-2
5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮物理化学性质
[ 密度 ]:
1.4±0.1 g/cm3
[ 沸点 ]:
312.2±52.0 °C at 760 mmHg
[ 熔点 ]:
206ºC (tech., 198-202ºC)
[ 分子式 ]:
C10H8ClN3O
[ 分子量 ]:
221.643
[ 闪点 ]:
142.6±30.7 °C
[ 精确质量 ]:
221.035583
[ PSA ]:
60.91000
[ LogP ]:
0.73
[ 外观性状 ]:
无色,无臭固体,(硬脂酸正丁酯,棕色,近乎于无臭固体)
[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C
[ 折射率 ]:
1.668
[ 储存条件 ]:
库房通风低温干燥,与食品原料分开储运
[ 水溶解性 ]:
水溶性：不溶；水溶解度：400 mg/l 20 °C；可溶于：甲醇；微溶：丙酮；不溶：二氯甲烷,苯,甲苯,氯仿,乙醚
5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UR6125000
- CHEMICAL NAME :
- 3(2H)-Pyridazinone, 5-amino-4-chloro-2-phenyl-
- CAS REGISTRY NUMBER :
- 1698-60-8
- BEILSTEIN REFERENCE NO. :
- 0397241
- LAST UPDATED :
- 199706
- DATA ITEMS CITED :
- 26
- MOLECULAR FORMULA :
- C10-H8-Cl-N3-O
- MOLECULAR WEIGHT :
- 221.66
- WISWESSER LINE NOTATION :
- T6NNVJ BR& DG EZ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 647 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >30800 mg/m3/4H
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 194 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1410 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 598 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 235 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1205 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - muscle contraction or spasticity
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 2500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 493 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 162 gm/kg/2Y-C
- TOXIC EFFECTS :
- Musculoskeletal - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 30 gm/kg/30D-I
- TOXIC EFFECTS :
- Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 6006 mg/kg/13W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Endocrine - changes in thyroid weight Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - transaminases
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 10 mg/m3/4H/17W-I
- TOXIC EFFECTS :
- Liver - other changes Blood - changes in other cell count (unspecified) Blood - changes in leukocyte (WBC) count
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 142 gm/kg/92W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 10 mg/m3/4H/17W-I
- TOXIC EFFECTS :
- Liver - other changes Blood - changes in other cell count (unspecified) Blood - changes in leukocyte (WBC) count
- TYPE OF TEST :
- TCLo - Lowest published toxic concentration
- ROUTE OF EXPOSURE :
- Inhalation
- DOSE :
- 1 mg/m3/4H
- SEX/DURATION :
- male 72 week(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intravenous
- DOSE :
- 175 mg/kg
- SEX/DURATION :
- female 8 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 50 mg/m3
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 50(1),80,1985 *** REVIEWS *** TOXICOLOGY REVIEW DTTIAF Deutsche Tieraerztliche Wochenschrift. (Hanover, Fed. Rep. Ger.) V.1-77, 1893-1970. Volume(issue)/page/year: 80,485,1973 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989
5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮安全信息
[ 符号 ]:
GHS07, GHS09
[ 信号词 ]:
Warning
[ 危害声明 ]:
H317-H410
[ 警示性声明 ]:
P273-P280-P501
[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ 危害码 (欧洲) ]:
Xi: Irritant;N: Dangerous for the environment;
[ 风险声明 (欧洲) ]:
R43;R50/53
[ 安全声明 (欧洲) ]:
S24-S37-S60-S61
[ 危险品运输编码 ]:
3077
[ RTECS号 ]:
UR6125000
[ 海关编码 ]:
2933990017
5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮合成路线
5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮上下游产品
5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮上游产品
5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮下游产品
5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮海关
[ 海关编码 ]: 2933990017
[ 中文概述 ]:
2933990017 唑草酯,四环唑,恶草酸等〔包括喹禾糠酯,哒草特,咯草隆,禾草敌,唑草胺,敌草快,氯草敏〕。监管条件:S(进出口农药登记证明)。增值税率:17.0%。退税率:9.0%。最低关税:6.5%。普通关税:20.0%
[ 申报要素 ]: 品名, 成分含量, 用途, 乌洛托品请注明外观, 6－己内酰胺请注明外观, 签约日期
[ 监管条件 ]: S.进出口农药登记证明
[ Summary ]:
2933990017 6,7-dihydrodipyrido[1,2-a:2',1'-c]pyrazine-5,8-diium bromide。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%
5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮文献
Environ. Sci. Pollut. Res. Int. 20(2) , 855-61, (2013)
Pesticides that contain a halogen functional group have been destructed by means of detonative combustion. The following compounds were examined: (1) atrazine-2-chloro-4-ethylamino-6-isopropylamino-1,...
Prevention of chloridazon and metribuzin pollution using lignin-based formulationsEnviron. Pollut. 158(5) , 1412-9, (2010)
The herbicides chloridazon and metribuzin, identified as groundwater pollutants, were incorporated in lignin-based granules with different sizes to obtain controlled release formulations (CRFs) and re...
Time- and dose-dependent induction of HSP70 in Lemna minor exposed to different environmental stressors.Bull. Environ. Contam. Toxicol. 87(3) , 226-30, (2011)
The objective of this study was to examine the influence of different stressors, including cadmium (heavy metal), anthracene (polycyclic aromatic hydrocarbon-PAH) and chloridazon (herbicide), on popul...
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产品详情：[Perfemiker]5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮,≥95 %
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[5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮]化源网提供5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮CAS号1698-60-8，5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮MSDS及其说明、性质、英文名、生产厂家、作用/用途、分子量、密度、沸点、熔点、结构式等。CAS号查询5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮上化源网，专业又轻松。>>电脑版：5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮
标题：1698-60-8_5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮CAS号:1698-60-8_5-氨基-4-氯-2-苯基-3(2H)-哒嗪酮【结构式 性质 英文】 - 化源网 地址：https://www.chemsrc.com/amp/cas/1698-60-8_820667.html