GSK-LSD1二盐酸盐

GSK-LSD1 is a potent and selective inhibitor of lysine specific demethylase 1 (LSD1). GSK-LSD1 potently inhibits proliferation of varies cancer cell lines by changing gene expression patterns. GSK-LSD1 inhibits LSD1 with an IC50 of 16 nM and is > 1000 fold selective over other closely related FAD utilizing enzymes (i.e. LSD2, MAO-A, MAO-B). GSK-LSD1 induces gene expression changes in cancer cell lines (average EC50 < 5 nM) and inhibits cancer cell line growth (average EC50 < 5 nM). Lysine specific demethylase 1 (LSD1) is a histone demethylase found in various transcriptional co-repressor complexes. LSD1 is involved in ES cell differentiation, hematopoiesis, and has been described as having a role in Acute Myeloid Leukemia (AML). (http://www.thesgc.org/chemical-probes/GSK-LSD1)

[ 分子式 ]:
C₁₄H₂₂Cl₂N₂

[ 分子量 ]:
289.244

[ 精确质量 ]:
288.115997

[ 储存条件 ]:
2-8°C，保存于惰性气体中

公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：GSK-LSD1二盐酸盐

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公司名：上海源溪生物科技有限公司

区域：上海市浦东新区

价格：
￥需询单/1g

联系人：赖经理

产品详情：GSK-LSD1 dihydrochloride

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公司名：上海创赛科技有限公司

区域：上海市嘉定区

价格：
￥681.0/1mg ￥1362.0/5mg ￥1947.0/10mg

联系人：夏言

产品详情：[Perfemiker]GSK-LSD1二盐酸盐,≥98%

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