fluorophenothiazine dihydrochloride

fluorophenothiazine dihydrochloride名称

[ CAS 号 ]:
1827-91-4

[ 英文名 ]:
fluorophenothiazine dihydrochloride

[英文别名 ]:

fluorophenothiazine dihydrochloride物理化学性质

[ 密度 ]:
1.256g/cm3

[ 沸点 ]:
600.4ºC at 760 mmHg

[ 分子式 ]:
C24H31ClF3N3O2S

[ 分子量 ]:
518.03500

[ 闪点 ]:
316.9ºC

[ 精确质量 ]:
517.17800

[ PSA ]:
64.48000

[ LogP ]:
5.06750

[ 蒸汽压 ]:
2.9E-15mmHg at 25°C

[ 折射率 ]:
1.567

fluorophenothiazine dihydrochloride毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KM5425000
CHEMICAL NAME :
Ethanol, 2-(2-(4-(3-(2-(trifluoromethyl)phenothiazin-10-yl)pro pyl)-1-piperazinyl)et hoxy)-, dihydrochloride
CAS REGISTRY NUMBER :
1827-91-4
LAST UPDATED :
199506
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C24-H30-F3-N3-O2-S.2Cl-H
MOLECULAR WEIGHT :
554.55
WISWESSER LINE NOTATION :
T C666 BN ISJ EXFFF B3- AT6N DNTJ D2O2Q &GH 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
588 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - chromodacryorrhea Sense Organs and Special Senses (Eye) - ptosis Behavioral - rigidity (including catalepsy)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
199 mg/kg
TOXIC EFFECTS :
Sense Organs and Special Senses (Eye) - chromodacryorrhea Sense Organs and Special Senses (Eye) - ptosis Behavioral - rigidity (including catalepsy)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
40 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - ataxia
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 136,476,1962

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