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河豚毒素柠檬酸盐

河豚毒素柠檬酸盐用途

Tetrodotoxin (TTx) is a potent, highly selective sodium channel blocker with IC50 of 33 nM for Nav1.6.

河豚毒素柠檬酸盐名称

[ CAS 号 ]:
18660-81-6

[ 中文名 ]:
河豚毒素鹼

[ 英文名 ]:
Tetrodotoxin citrate

[中文别名 ]:

河豚毒素柠檬酸盐

河豚毒素柠檬酸盐物理化学性质

[ 沸点 ]:
772.1ºC at 760 mmHg

[ 分子式 ]:
C₁₇H₂₅N₃O₁₅

[ 分子量 ]:
511.39200

[ 闪点 ]:
420.7ºC

[ 精确质量 ]:
511.12900

[ PSA ]:
319.88000

[ 蒸汽压 ]:
1.58E-27mmHg at 25°C

[ 储存条件 ]:
Desiccate at -20°C

河豚毒素柠檬酸盐毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XF8884500

CAS REGISTRY NUMBER :: 18660-81-6

LAST UPDATED :: 198611

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C11-H17-N3-O8.xC6-H8-O7

MOLECULAR WEIGHT :: 1664.29

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 8 ng/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AFMMBW Archivos de la Facultad de Medicina de Madrid. (Madrid, Spain) V.1-40, 1961-81. Volume(issue)/page/year: 8,151,1965

河豚毒素柠檬酸盐安全信息

[ 危害码 (欧洲) ]:
T+

[ 风险声明 (欧洲) ]:
26/27/28

[ 安全声明 (欧洲) ]:
22-36/37/39-45

[ RTECS号 ]:
IO1450000