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苯并[C]屈

苯并[C]屈名称

[ CAS 号 ]:
194-69-4

[ 中文名 ]:
苯并[C]屈

[ 英文名 ]:
Benzo[c]chrysene

[英文别名 ]:

1,2:5,6-Dibenzophenanthrene
benz<c>chrysene
Benzo[c]chrysene
1,2,5,6-Dibenzphenanthrene

苯并[C]屈物理化学性质

[ 密度 ]:
1.2±0.1 g/cm3

[ 沸点 ]:
524.7±17.0 °C at 760 mmHg

[ 熔点 ]:
126.5°C

[ 分子式 ]:
C₂₂H₁₄

[ 分子量 ]:
278.347

[ 闪点 ]:
264.5±15.1 °C

[ 精确质量 ]:
278.109558

[ LogP ]:
7.14

[ 蒸汽压 ]:
0.0±0.7 mmHg at 25°C

[ 折射率 ]:
1.812

[ 储存条件 ]:
通风低温干燥

苯并[C]屈毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE7350000

CHEMICAL NAME :: Benzo(c)chrysene

CAS REGISTRY NUMBER :: 194-69-4

BEILSTEIN REFERENCE NO. :: 1876196

LAST UPDATED :: 199710

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C22-H14

MOLECULAR WEIGHT :: 278.36

WISWESSER LINE NOTATION :: L F6 C6 B666J

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1630 mg/kg/68W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

REFERENCE :: PRLBA4 Proceedings of the Royal Society of London, Series B: Biological Sciences. (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 1905- Volume(issue)/page/year: 129,439,1940

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2400 mg/kg/36W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Tumorigenic - tumors at site of application

REFERENCE :: PRLBA4 Proceedings of the Royal Society of London, Series B: Biological Sciences. (Royal Soc., 6 Carlton House Terrace, London SW1Y 5AG, UK) V.76- 1905- Volume(issue)/page/year: 129,439,1940

苯并[C]屈安全信息

[ 海关编码 ]:
2902909090

苯并[C]屈合成路线

详细合成路线

苯并[C]屈上下游产品

苯并[C]屈上游产品

苯并[C]屈下游产品

苯并[C]屈海关

[ 海关编码 ]: 2902909090

[ 中文概述 ]:
2902909090. 其他芳香烃. 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:2.0%. 普通关税:30.0%

[ 申报要素 ]: 品名, 成分含量

[ Summary ]:
2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

苯并[C]屈文献

Covalent DNA adducts formed by benzo[c]chrysene in mouse epidermis and by benzo[c]chrysene fjord-region diol epoxides reacted with DNA and polynucleotides.

Chem. Res. Toxicol. 10(11) , 1275-84, (1997)

The metabolic activation in mouse skin of benzo[c]chrysene (B[c]C), a weakly carcinogenic polycyclic aromatic hydrocarbon (PAH) present in coal tar and crude oil, was investigated. Male Parkes mice we...

Metabolism of benzo[c]chrysene and comparative mammary gland tumorigenesis of benzo[c]chrysene bay and fjord region diol epoxides in female CD rats.

Chem. Res. Toxicol. 16(2) , 227-31, (2003)

Benzo[c]chrysene (BcC), an environmental pollutant, is a unique polycyclic aromatic hydrocarbon that possesses both a bay region and a fjord region in the same molecule. We previously demonstrated tha...

Synthesis of fjord region tetraols and their use in hepatic biotransformation studies of dihydrodiols of benzo[c]chrysene, benzo[g]chrysene and dibenzo[a,l]pyrene.

Carcinogenesis 19(4) , 639-48, (1998)

Metabolic activation of the racemic benzo[c]chrysene-trans-9,10-, benzo[g]chrysene-trans-11,12- and dibenzo[a,l]pyrene-trans-11,12-dihydrodiols to fjord region syn- and anti-dihydrodiol epoxides by mi...

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