Piperazine,1,4-bis[bis(1-aziridinyl)phosphinothioyl]-
名称
[ CAS 号 ]:
1950-08-9
[ 英文名 ]:
Piperazine,1,4-bis[bis(1-aziridinyl)phosphinothioyl]-
[英文别名 ]:
- Thiodipin
- Thiodipine
- 1,4-Bis-(diethylenimino-thiophosphono)-piperazin
- 35P-Thiodipin
物理化学性质
[ 分子式 ]:
C12H24N6P2S2
[ 分子量 ]:
378.43700
[ 精确质量 ]:
378.09800
[ PSA ]:
102.32000
[ LogP ]:
1.24400
[ 蒸汽压 ]:
7.04E-10mmHg at 25°C
毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TK8720000
- CHEMICAL NAME :
- Piperazine, 1,4-bis(bis(1-aziridinyl)phosphinothioyl)-
- CAS REGISTRY NUMBER :
- 1950-08-9
- BEILSTEIN REFERENCE NO. :
- 0629376
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C12-H24-N6-P2-S2
- MOLECULAR WEIGHT :
- 378.48
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg/10D-I
- TOXIC EFFECTS :
- Endocrine - changes in spleen weight Endocrine - changes in thymus weight Related to Chronic Data - death
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,732,1961
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 1 gm/kg/10D-I
- TOXIC EFFECTS :
- Blood - leukopenia Related to Chronic Data - death
- REFERENCE :
- FATOAO Farmakologiya i Toksikologiya (Moscow). For English translation, see PHTXA6 and RPTOAN. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.2- 1939- Volume(issue)/page/year: 24,732,1961
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