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2-氨基-4-苯基噻唑

2-氨基-4-苯基噻唑名称

[ CAS 号 ]:
2010-06-2

[ 中文名 ]:
2-氨基-4-苯基噻唑

[ 英文名 ]:
4-Phenyl-1,3-thiazol-2-amine

[中文别名 ]:

2-氨基苯噻唑

[英文别名 ]:

MFCD00039680
2-Thiazolamine,4-phenyl
4-phenyl-2-aminothiazole
2-Amino-4-phenyl-1,3-thiazole
4-Phenyl-1,3-thiazol-2-amine
2-amino-4-phenylthiazol
4-Phenyl-2-thiazolylamine
Phenthiazamine
4-Phenylthiazol-2-amine
2-Amino-4-phenylthiazole

2-氨基-4-苯基噻唑物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
363.4±11.0 °C at 760 mmHg

[ 熔点 ]:
149-153 °C(lit.)

[ 分子式 ]:
C₉H₈N₂S

[ 分子量 ]:
176.238

[ 闪点 ]:
173.6±19.3 °C

[ 精确质量 ]:
176.040817

[ PSA ]:
67.15000

[ LogP ]:
2.14

[ 外观性状 ]:
固体;White to Light yellow to Light orange powder to crystal

[ 蒸汽压 ]:
0.0±0.8 mmHg at 25°C

[ 折射率 ]:
1.660

[ 储存条件 ]:
室温

2-氨基-4-苯基噻唑毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ2878000

CHEMICAL NAME :: Thiazole, 2-amino-4-phenyl-

CAS REGISTRY NUMBER :: 2010-06-2

LAST UPDATED :: 199706

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C9-H8-N2-S

MOLECULAR WEIGHT :: 176.25

WISWESSER LINE NOTATION :: T5N CSJ BZ ER

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: EPXXDW European Patent Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #0001727

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 320 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00815

2-氨基-4-苯基噻唑安全信息

[ 符号 ]:

GHS05, GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H301-H315-H318-H335

[ 警示性声明 ]:
P261-P280-P301 + P310-P305 + P351 + P338

[ 个人防护装备 ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ 危害码 (欧洲) ]:
Xn: Harmful;Xi: Irritant;

[ 风险声明 (欧洲) ]:
R22

[ 安全声明 (欧洲) ]:
S26-S36/37/39

[ 危险品运输编码 ]:
UN 2811 6.1 / PGIII

[ WGK德国 ]:
3

[ RTECS号 ]:
XJ2878000

[ 海关编码 ]:
2934100090

2-氨基-4-苯基噻唑合成路线

详细合成路线

2-氨基-4-苯基噻唑海关

[ 海关编码 ]: 2934100090

[ 中文概述 ]:
2934100090. 结构上含有一个非稠合噻唑环的化合物(不论是否氢化). 增值税率:17.0%. 退税率:9.0%. 监管条件:无. 最惠国关税:6.5%. 普通关税:20.0%

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

2-氨基-4-苯基噻唑文献

Pharmacological analysis of the mechanism of action of phenthiazamine, a piscine anesthetic.

J. Pharmacobiodyn. 3(2) , 85-93, (1980)

Phenthiazamine was developed by Sekizawa et al. as a centrally acting anesthetic for fish. Frog sympathetic ganglion was used as a model to elucidate the mechanism of its anesthetic action. The positi...

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