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降钙素,人

降钙素,人用途

降钙素是一种内源性降钙素受体降钙素激动剂人体降低全身血钙水平,抑制骨吸收。

降钙素,人名称

[ CAS 号 ]:
21215-62-3

[ 中文名 ]:
人体重组型降钙素

[ 英文名 ]:
Calcitonin (human) trifluoroacetate salt

[中文别名 ]:

降钙素,人

[英文别名 ]:

calcitonin, human
MFCD00167520
EINECS 244-276-2

降钙素,人生物活性

[ 描述 ]:

降钙素是一种内源性降钙素受体降钙素激动剂人体降低全身血钙水平,抑制骨吸收。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> CGRP受体

信号通路 >> 神经信号通路 >> CGRP受体

降钙素,人物理化学性质

[ 分子式 ]:
C₁₅₁H₂₂₆N₄₀O₄₅S₃

[ 分子量 ]:
3417.85000

[ 精确质量 ]:
3415.58000

[ PSA ]:
1435.50000

[ 外观性状 ]:
白色冻干的粉末

[ 储存条件 ]:
-20°C

降钙素,人安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危害码 (欧洲) ]:
Xi

[ 安全声明 (欧洲) ]:
S22-S24/25

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

降钙素,人文献

Inhibitory effects of magnolol and honokiol on human calcitonin aggregation.

Sci. Rep. 5 , 13556, (2015)

Amyloid formation is associated with multiple amyloidosis diseases. Human calcitonin (hCT) is a typical amyloidogenic peptide, its aggregation is associated with medullary carcinoma of the thyroid (MT...

STC1 interference on calcitonin family of receptors signaling during osteoblastogenesis via adenylate cyclase inhibition.

Mol. Cell. Endocrinol. 403 , 78-87, (2015)

Stanniocalcin 1 (STC1) and calcitonin gene-related peptide (CGRP) are involved in bone formation/remodeling. Here we investigate the effects of STC1 on functional heterodimer complex CALCRL/RAMP1, exp...

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