Pyridine,3-(3,3-dimethyl-1-triazen-1-yl)-, 1-oxide

名称

[ CAS 号 ]:
21600-42-0

[ 英文名 ]:
Pyridine,3-(3,3-dimethyl-1-triazen-1-yl)-, 1-oxide

[英文别名 ]:

Pyndt

物理化学性质

[ 密度 ]:
1.16g/cm3

[ 沸点 ]:
335ºC at 760mmHg

[ 分子式 ]:
C₇H₁₀N₄O

[ 分子量 ]:
166.18000

[ 闪点 ]:
156.4ºC

[ 精确质量 ]:
166.08500

[ PSA ]:
53.42000

[ LogP ]:
1.67540

[ 蒸汽压 ]:
0.000124mmHg at 25°C

[ 折射率 ]:
1.566

毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XY2300000

CHEMICAL NAME :: Triazene, 3,3-dimethyl-1-(m-pyridyl-N-oxide)-

CAS REGISTRY NUMBER :: 21600-42-0

LAST UPDATED :: 199709

DATA ITEMS CITED :: 13

MOLECULAR FORMULA :: C7-H10-N4-O

MOLECULAR WEIGHT :: 166.21

WISWESSER LINE NOTATION :: T6NJ AO CNUNN1&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 230 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 490 mg/kg/38W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Brain and Coverings - tumors Peripheral Nerve and Sensation - peripheral nerve tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 540 mg/kg/36W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Brain and Coverings - tumors

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Heritable translocation test

MUTATION DATA

TYPE OF TEST :: Host-mediated assay

TEST SYSTEM :: Rodent - mouse Yeast - Saccharomyces cerevisiae

DOSE/DURATION :: 400 umol/kg

REFERENCE :: AGACBH Agents and Actions, A Swiss Journal of Pharmacology. (Birkhaeuser Verlag, POB 133, CH-4010 Basel, Switzerland) V.1- 1969/70- Volume(issue)/page/year: 3,99,1973