硫甲睾酮
硫甲睾酮名称
[ CAS 号 ]:
2205-73-4
[ 中文名 ]:
硫甲睾酮
[ 英文名 ]:
S-[(1S,7R,8S,9S,10R,13S,14S,17S)-1-acetylsulfanyl-17-hydroxy-10,13,17-trimethyl-3-oxo-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-7-yl] ethanethioate
[英文别名 ]:
- STA-307
- Thiomestrone
- Emdabol
- Emdabolin
- Embadol
- Tiomesterona [INN-Spanish]
- Protabol
- Tiomesteronum [INN-Latin]
- Tiomesterone
- Thiomesterone
硫甲睾酮物理化学性质
[ 密度 ]:
1.25g/cm3
[ 沸点 ]:
588.1ºC at 760mmHg
[ 分子式 ]:
C24H34O4S2
[ 分子量 ]:
450.65400
[ 闪点 ]:
309.5ºC
[ 精确质量 ]:
450.19000
[ PSA ]:
122.04000
[ LogP ]:
4.78570
[ 蒸汽压 ]:
2.79E-16mmHg at 25°C
[ 折射率 ]:
1.595
硫甲睾酮毒性和生态
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BV8396900
- CHEMICAL NAME :
- Androst-4-en-3-one, 17-beta-hydroxy-1-alpha,7-alpha-dimercapto-17-methyl- , 1,7-diacetate
- CAS REGISTRY NUMBER :
- 2205-73-4
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C24-H34-O4-S2
- MOLECULAR WEIGHT :
- 450.70
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,330,1964 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 200 mg/kg
- SEX/DURATION :
- male 10 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,330,1964
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 200 mg/kg
- SEX/DURATION :
- female 10 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,330,1964
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相关化合物
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