罗美昔布

罗美昔布用途

Lumiracoxib, also known as CGS 35189 and COX 189, is a COX-2 selective inhibitor non-steroidal anti-inflammatory drug, manufactured by Novartis and still sold in few countries, including Mexico, Ecuador and the Dominican Republic, under the trade name Prexige. Since its original approval, lumiracoxib has been withdrawn from the market in several countries, mostly due to its potential for causing liver failure (sometimes requiring liver transplantation). It has never been approved for use in the United States.

罗美昔布名称

[ CAS 号 ]:
220991-20-8

[ 中文名 ]:
罗美昔布

[ 英文名 ]:
Lumiracoxib

[中文别名 ]:

[英文别名 ]:

Prexige (Novartis)
Prexige
COX189
Joicela
Lumiracoxib
[14C]-Lumiracoxib
Lumiracoxib [USAN:INN]

罗美昔布物理化学性质

[ 密度 ]:
1.4±0.1 g/cm3

[ 沸点 ]:
395.7±42.0 °C at 760 mmHg

[ 熔点 ]:
139-141ºC

[ 分子式 ]:
C₁₅H₁₃ClFNO₂

[ 分子量 ]:
293.721

[ 闪点 ]:
193.1±27.9 °C

[ 精确质量 ]:
293.061890

[ PSA ]:
49.33000

[ LogP ]:
3.90

[ 外观性状 ]:
淡黄色固体

[ 蒸汽压 ]:
0.0±1.0 mmHg at 25°C

[ 折射率 ]:
1.628

[ 储存条件 ]:
-20°C Freezer

罗美昔布

罗美昔布用途

罗美昔布名称

罗美昔布物理化学性质

罗美昔布合成路线

详细合成路线

罗美昔布上下游产品

罗美昔布上游产品

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