柯里拉京

Corilagin 是一种鞣酸,可从 Caesalpinia coriaria (Jacq.) 分离出来。Corilagin 抑制 RNA 肿瘤病毒逆转录酶的活性。Corilagin 抑制金黄色葡萄球菌的生长,MIC 为 25 μg/mL。Corilagin 对肝癌和卵巢癌具有良好的抗肿瘤活性,而对正常细胞和组织的毒性很低。

[ 描述 ]:

[ 相关类别 ]:

[参考文献]

[ 密度 ]:
2.1±0.1 g/cm3

[ 沸点 ]:
1280.8±65.0 °C at 760 mmHg

[ 熔点 ]:
>200ºC dec

[ 分子式 ]:
C₂₇H₂₂O₁₈

[ 分子量 ]:
634.453

[ 闪点 ]:
418.8±27.8 °C

[ 精确质量 ]:
634.080627

[ PSA ]:
310.66000

[ LogP ]:
2.34

[ 外观性状 ]:
灰白色固体

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.881

[ 储存条件 ]:
-20°C Freezer

[ 水溶解性 ]:
H2O: soluble1mg/mL, clear, colorless

详细MSDS(安全技术说明书)

[ 危险品运输编码 ]:
NONH for all modes of transport

详细合成路线

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Mechanisms of action of corilagin and tellimagrandin I that remarkably potentiate the activity of beta-lactams against methicillin-resistant Staphylococcus aureus.

Microbiol. Immunol. 48(1) , 67-73, (2004)

Corilagin and tellimagrandin I are polyphenols isolated from the extract of Arctostaphylos uvaursi and Rosa canina L. (rose red), respectively. We have reported that corilagin and tellimagrandin I rem...

Inhibitory effect of the gallotannin corilagin on dextran sulfate sodium-induced murine ulcerative colitis.

J. Nat. Prod. 76(11) , 2120-5, (2013)

The therapeutic effect of corilagin (1) was evaluated in an acute colitis model induced by dextran sulfate sodium (DSS) in mice, and the mechanism of action was investigated in this study. Animals wer...

Modulation of PAI-1 and tPA activity and thrombolytic effects of corilagin.

Planta Med. 69(12) , 1109-12, (2003)

In this study, Charlton's and Tomihisa's methods were modified to investigate the thrombolytic effect of corilagin from the Chinese herbal plant Phyllanthus urinaria L., as well as its effect on carot...

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公司名：上海化源世纪贸易有限公司

区域：上海市普陀区

价格：

联系人：徐经理

产品详情：柯里拉京

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公司名：云南西力生物技术股份有限公司

区域：昆明市盘龙区

价格：
￥需询单/5mg

联系人：郑雪平

产品详情：柯里拉京

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公司名：上海吉至生化科技有限公司

区域：上海市奉贤区

价格：
￥788.0/20mg

联系人：刘佳

产品详情：柯里拉京

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公司名：上海脉铂医药科技有限公司

区域：上海市嘉定区

价格：
￥1489.0/20mg ￥需询单/1g ￥需询单/1g ￥需询单/1g

联系人：李先生

产品详情：Corilagin

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公司名：上海阿拉丁生化科技股份有限公司

区域：上海市浦东新区

价格：
￥308.9/5mg ￥2677.9/100mg ￥1029.9/25mg ￥1647.9/50mg

联系人：阿拉丁

产品详情：Corilagin

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