2-甲基-6-乙基苯胺

2-甲基-6-乙基苯胺用途

【用途一】
是重要的农药、染料及医药中间体，是酰胺类除草剂乙草胺的生产原料
【用途二】
2-甲基-6-乙基苯胺是除草剂乙草胺、异丙甲草胺、异丙草胺等的中间体。
【用途三】
重要的农药、染料及医药中间体，农药方面是生产除草剂丁草胺的关键中间体，是氯代酰胺类除草剂乙草胺和异丙甲草胺的重要中间体。也可用于其它有机合成。
【用途四】
生产除草剂乙草胺和异丙甲草胺的关键原料，也可用合成染料、环氧树脂固化剂等。

2-甲基-6-乙基苯胺名称

[ CAS 号 ]:
24549-06-2

[ 中文名 ]:
2-甲基-6-乙基苯胺

[ 英文名 ]:
2-Ethyl-6-methylaniline

[中文别名 ]:

[英文别名 ]:

EINECS 246-309-6
2-Methyl-6-ethylaniline
2-Ethyl-6-methylaniline
6-Ethyl-2-toluidine
Benzenamine,2-ethyl-6-methyl
o-Toluidine,6-ethyl
ZR B2 F1
2-ethyl-6-methyl-phenylamine
2-Ethyl-6-methylbenzenamine
6-Ethyl-o-toluidine

2-甲基-6-乙基苯胺物理化学性质

[ 密度 ]:
1.0±0.1 g/cm3

[ 沸点 ]:
228.3±9.0 °C at 760 mmHg

[ 熔点 ]:
−33 °C(lit.)

[ 分子式 ]:
C₉H₁₃N

[ 分子量 ]:
135.206

[ 闪点 ]:
89.4±0.0 °C

[ 精确质量 ]:
135.104797

[ PSA ]:
26.02000

[ LogP ]:
2.39

[ 外观性状 ]:
液体

[ 蒸汽压 ]:
0.1±0.5 mmHg at 25°C

[ 折射率 ]:
1.550

[ 储存条件 ]:
-20°C

2-甲基-6-乙基苯胺MSDS

详细MSDS(安全技术说明书)

2-甲基-6-乙基苯胺毒性和生态

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BY5600000

CHEMICAL NAME :: Aniline, 2-methyl-6-ethyl-

CAS REGISTRY NUMBER :: 24549-06-2

BEILSTEIN REFERENCE NO. :: 2079468

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C9-H13-N

MOLECULAR WEIGHT :: 135.23

WISWESSER LINE NOTATION :: ZR B2 F1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 885 mg/kg

TOXIC EFFECTS :: Liver - other changes Blood - changes in bone marrow (not otherwise specified) Blood - changes in spleen

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2200 mg/m3/4H

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - effect, not otherwise specified Lungs, Thorax, or Respiration - dyspnea Nutritional and Gross Metabolic - weight loss or decreased weight gain

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 930 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - muscle weakness Behavioral - ataxia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 700 mg/kg

TOXIC EFFECTS :: Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - muscle weakness Behavioral - ataxia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2210 mg/kg/10D-C

TOXIC EFFECTS :: Blood - changes in bone marrow (not otherwise specified)

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 10200 mg/kg/6W-I

TOXIC EFFECTS :: Kidney, Ureter, Bladder - other changes in urine composition Blood - changes in erythrocyte (RBC) count Nutritional and Gross Metabolic - changes in chlorine

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 8300 nmol/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 211,279,1988

2-甲基-6-乙基苯胺安全信息

[ 符号 ]:

GHS06

[ 信号词 ]:
Danger

[ 危害声明 ]:
H302-H331

[ 警示性声明 ]:
P261-P311

[ 个人防护装备 ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ 危害码 (欧洲) ]:
Xn:Harmful

[ 风险声明 (欧洲) ]:
R20/21/22

[ 安全声明 (欧洲) ]:
S24/25-S23

[ 危险品运输编码 ]:
2810

[ WGK德国 ]:
2

[ RTECS号 ]:
BY5600000

[ 包装等级 ]:
II

[ 危险类别 ]:
6.1

[ 海关编码 ]:
2933990090

2-甲基-6-乙基苯胺合成路线

详细合成路线

2-甲基-6-乙基苯胺上下游产品

2-甲基-6-乙基苯胺上游产品

2-甲基-6-乙基苯胺下游产品

2-甲基-6-乙基苯胺制备

以邻甲基苯胺为原料，与乙烯进行邻位烷基化而得。原料消耗定额：邻甲苯胺（99%）990kg/t、乙烯（99%）330kg/t、催化剂原料（99.5%）15kg/t、氮气（99%）30m3/t。

2-甲基-6-乙基苯胺海关

[ 海关编码 ]: 2921493000

[ 申报要素 ]: 品名, 成分含量, 用途

[ Summary ]:
HS: 2921493000. 2-ethyl-6-methylaniline. VAT:17.0%. tax rebate rate:9.0%. supervision conditions:None. MFN tarrif:4.0%. general tariff:11.0%

2-甲基-6-乙基苯胺文献

Degradation and leaching of the herbicides metolachlor and diuron: a case study in an area of Northern Italy.

Environ. Pollut. 134(3) , 525-34, (2005)

In this work the degradation of the herbicides metolachlor, diuron, monuron and of the metabolites 2-ethyl-6-methylaniline (EMA), and 3,4-dichloroaniline (DCA) was assessed in laboratory experiments o...

Resolution of< i> N</i>-(2-ethyl-6-methylphenyl) alanine via free and immobilized lipase from< i> Pseudomonas cepacia</i>. Zheng L, et al.

J. Mol. Catal., B Enzym. 38(3) , 119-25, (2006)

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