芹菜苷

芹菜苷用途

Apiin 是 Apium graveolens 叶片的主要成分之一,具有抗炎特性。Apiin 在体外能抑制亚硝酸盐 (NO) 的产生 (IC50 = 0.08 mg/mL),在 LPS 激活的 J774.A1 细胞中能抑制 iNOS 的表达 (IC50 = 0.049 mg/ mL) 。

芹菜苷名称

[ CAS 号 ]:
26544-34-3

[ 中文名 ]:
芹菜甙

[ 英文名 ]:
Apiin

[中文别名 ]:

[英文别名 ]:

APIIN
Apioside
APIGENIN-7-APIOGLUCOSIDE
apigenin-7-O-apiosyl(1->2)glucoside
apigenin 7-O-apiosylglucoside
4',5,7-Trihydroxyflavone-7-apiosylglucoside
7-(2-APIOSYLGLUCOSYL)APIGENIN
Apigenin-7-(2-O-apiosylglucoside)
Apigenin-7-apiosylglucoside
EINECS 247-780-0

芹菜苷生物活性

[ 描述 ]:

[ 相关类别 ]:

信号通路 >> 其他 >> 其他

研究领域 >> 炎症/免疫

[参考文献]

[1]. Mencherini T, et al. An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties. J Pharm Pharmacol. 2007 Jun;59(6):891-7.

芹菜苷物理化学性质

[ 密度 ]:
1.7±0.1 g/cm3

[ 沸点 ]:
942.2±65.0 °C at 760 mmHg

[ 熔点 ]:
230ºC (dec.)

[ 分子式 ]:
C₂₆H₂₈O₁₄

[ 分子量 ]:
564.492

[ 闪点 ]:
316.7±27.8 °C

[ 精确质量 ]:
564.147888

[ PSA ]:
228.97000

[ LogP ]:
0.74

[ 蒸汽压 ]:
0.0±0.3 mmHg at 25°C

[ 折射率 ]:
1.744

[ 储存条件 ]:
2-8C

芹菜苷MSDS

详细MSDS(安全技术说明书)

芹菜苷安全信息

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
1

[ 海关编码 ]:
29389090

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芹菜苷文献

Evaluation of detection sensitivity in comprehensive two-dimensional liquid chromatography separations of an active pharmaceutical ingredient and its degradants.

Anal. Bioanal. Chem 407(1) , 265-77, (2015)

In this paper, we describe the findings of a study aimed at assessing the detection sensitivity of comprehensive two-dimensional high-performance liquid chromatography (LCxLC) separation of a degraded...

Bioavailability of apigenin from apiin-rich parsley in humans.

Ann. Nutr. Metab. 50(3) , 167-72, (2006)

Absorption and excretion of apigenin after the ingestion of apiin-rich food, i.e. parsley, was tested.Eleven healthy subjects (5 women, 6 men) in the age range of 23-41 years and with an average body ...

[Studies on the chemical constituents of the aerial parts of Seseli mairei].

Zhong Yao Cai 30(1) , 42-4, (2007)

To study the chemical constituents of the aerial parts of Seseli mairei Wolf.The chemical constituents have been separated with manifold chromatography methods, and their structures were determined hy...

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芹菜苷