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甲基泼尼松龙琥珀酸酯

甲基泼尼松龙琥珀酸酯用途

Methylprednisolone succinate 是一种合成的糖皮质激素,被广泛用作抗炎剂。

甲基泼尼松龙琥珀酸酯名称

[ CAS 号 ]:
2921-57-5

[ 中文名 ]:
甲基泼尼松龙琥珀酸酯

[ 英文名 ]:
Methylprednisolone succinate

[中文别名 ]:

[英文别名 ]:

Urbason-Soluble
methylprednisolone 21-hemisuccinate
MFCD00271782
Methylprednisolone sodium hemisuccinate
6-methylprednisolone-21-hemisuccinate
methylprednisolone hemisuccinate esters
Methylprednisolone hydrogen succinate
Solumedrol
EINECS 220-863-9
UNII-5GMR90S4KN

甲基泼尼松龙琥珀酸酯生物活性

[ 描述 ]:

Methylprednisolone succinate 是一种合成的糖皮质激素,被广泛用作抗炎剂。

[ 相关类别 ]:

信号通路 >> G 蛋白偶联受体/G 蛋白 >> 糖皮质激素受体

研究领域 >> 癌症

研究领域 >> 炎症/免疫

[ 靶点 ]

glucocorticoid receptor[1]

[参考文献]

[1]. Marchant A, et al. Methylprednisolone differentially regulates IL-10 and tumour necrosis factor (TNF) productionduring murine endotoxaemia. Clin Exp Immunol. 1996 Oct;106(1):91-6.

[2]. Diem R, et al. Methylprednisolone increases neuronal apoptosis during autoimmune CNS inflammation by inhibition of an endogenous neuroprotective pathway. J Neurosci. 2003 Aug 6;23(18):6993-7000.

[相关活性小分子]

甲基泼尼松龙琥珀酸酯物理化学性质

[ 密度 ]:
1.3±0.1 g/cm3

[ 沸点 ]:
689.6±55.0 °C at 760 mmHg

[ 分子式 ]:
C₂₆H₃₄O₈

[ 分子量 ]:
474.543

[ 闪点 ]:
230.7±25.0 °C

[ 精确质量 ]:
474.225372

[ PSA ]:
138.20000

[ LogP ]:
2.69

[ 蒸汽压 ]:
0.0±4.9 mmHg at 25°C

[ 折射率 ]:
1.593

[ 储存条件 ]:
2-8℃

甲基泼尼松龙琥珀酸酯安全信息

[ 危险品运输编码 ]:
NONH for all modes of transport

[ 海关编码 ]:
2942000000

甲基泼尼松龙琥珀酸酯合成路线

详细合成路线

甲基泼尼松龙琥珀酸酯海关

[ 海关编码 ]: 2942000000

甲基泼尼松龙琥珀酸酯文献

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Foot (Edinb.) 22(3) , 141-5, (2012)

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