(+)-BETA-HYDRASTINE

[ 密度 ]:
1.339g/cm3

[ 沸点 ]:
548.8ºC at 760mmHg

[ 分子式 ]:
C₂₁H₂₁NO₆

[ 分子量 ]:
383.39500

[ 闪点 ]:
285.7ºC

[ 精确质量 ]:
383.13700

[ PSA ]:
66.46000

[ LogP ]:
2.81110

[ 蒸汽压 ]:
4.28E-12mmHg at 25°C

[ 折射率 ]:
1.614

[ 个人防护装备 ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ 危险品运输编码 ]:
NONH for all modes of transport

[ WGK德国 ]:
3

Expanding the repertoire of small molecule transcriptional activation domains.

Bioorg. Med. Chem. 17 , 1034-43, (2009)

Molecules that can reconstitute the function of transcriptional activators hold enormous potential as therapeutic agents and as mechanistic probes. Previously we described an isoxazolidine bearing fun...

Differential modulation of respiratory neuronal discharge patterns by GABA(A) receptor and apamin-sensitive K(+) channel antagonism.

J. Neurophysiol. 86(5) , 2363-73, (2001)

The discharge patterns of respiratory neurons of the caudal ventral respiratory group (cVRG) appear to be subject to potent GABAergic gain modulation. Local application of the GABA(A) receptor antagon...

Effects of (1R,9S)-beta-hydrastine on l-DOPA-induced cytotoxicity in PC12 cells.

Eur. J. Pharmacol. 488(1-3) , 71-7, (2004)

(1R,9S)-beta-Hydrastine in lower concentrations of 10-50 microM inhibits dopamine biosynthesis in PC12 cells. In this study, the effects of (1R,9S)-beta-hydrastine on L-DOPA (L-3,4-dihydroxyphenylalan...

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